Guardant Health's Shield CRC Blood Test Achieves 95% Adherence Rate in Real-World Study of 20,000 Patients

Wednesday, Nov 5, 2025 4:07 pm ET1min read

Guardant Health announced new real-world data showing that its Shield blood-based screening test for colorectal cancer demonstrated patient adherence of 95% in a study of 20,000 patients. Shield is the first blood test to receive FDA approval as a primary screening option for CRC in average-risk adults aged 45 and older. The study found that Shield had an adherence rate of 98.5% in a separate study in Appalachia, increasing overall screening rates for CRC from 45% to 90%.

Guardant Health's Shield CRC Blood Test Achieves 95% Adherence Rate in Real-World Study of 20,000 Patients

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