Gain Therapeutics reports CNS target engagement with GCase substrate reduction.
ByAinvest
Thursday, Dec 18, 2025 7:10 am ET1min read
GANX--
• CNS target engagement confirmed with reduction in GluSph in CSF • GluSph reduction indicates increased GCase activity in the brain • Expected to impact Parkinson’s disease progression • KOL event planned for early January • First-ever observation of GCase modulator in PD patients • Gain Therapeutics provided evidence of reduced GluSph in CSF • Registration information available for KOL event.
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