Gain Therapeutics reports 81% decrease in GluSph with GT-02287 treatment.
ByAinvest
Tuesday, Jan 6, 2026 7:08 am ET1min read
GANX--
Gain Therapeutics reported a significant decrease in glucosylsphingosine (GluSph) levels in cerebrospinal fluid of Parkinson's disease patients treated with GT-02287, a GCase modulator. The reduction was 81% after 90 days of treatment. Elevated GluSph is associated with GCase dysfunction, alpha synuclein aggregation, and impaired mitochondrial function. These findings support the disease-modifying potential of GT-02287.
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