Fortress Biotech to Benefit from Crystalys' $205M Funding for Gout Treatment
ByAinvest
Wednesday, Oct 1, 2025 6:10 pm ET1min read
FBIO--
Crystalys, which acquired dotinurad from Urica Therapeutics in exchange for equity and a 3% royalty on future net sales, raised the funds to support global pivotal trials. The financing round was co-led by Novo Holdings, SR One, and Catalys Pacific, with participation from a broad syndicate of investors [1].
Urica Therapeutics retains an equity position in Crystalys and is entitled to a 3% royalty on future net sales of dotinurad. This strategic move by Urica is expected to enhance value for its parent company, Fortress Biotech, which holds a majority stake in Urica. The successful Series A financing by Crystalys is a strong endorsement of dotinurad's potential and supports the advancement of its clinical trials [1].
Fortress Biotech, the majority owner of Urica, has a strategic position in the biotechnology sector. Recently, Fortress achieved key milestones, including the acquisition of its subsidiary Checkpoint Therapeutics by Sun Pharma, which delivered approximately $28 million upfront [1]. Fortress' model focuses on leveraging its significant biopharmaceutical industry expertise and network to expand and advance its portfolio of product opportunities.
The significant reliance on external funding through a Series A financing round raises concerns about Urica's own financial stability and resource allocation for the development of its other assets. Forward-looking statements indicate multiple risks and uncertainties surrounding regulatory approval and commercialization, which could severely impact Urica's future earnings and stock price [1].
Urica Therapeutics, a minority stakeholder in Crystalys Therapeutics, is set to benefit from future global sales royalties after Crystalys secured $205 million in Series A funding for its gout treatment, dotinurad. The funding will advance Phase 3 trials for the treatment. Fortress Biotech, the majority owner of Urica, holds a strategic position in the biotechnology sector.
Urica Therapeutics, a minority stakeholder in Crystalys Therapeutics, is poised to benefit from future global sales royalties following Crystalys' securing of $205 million in Series A funding for its gout treatment, dotinurad. The funding will advance Phase 3 trials for the treatment, which has shown promising safety and efficacy in prior studies across several Asian countries [1].Crystalys, which acquired dotinurad from Urica Therapeutics in exchange for equity and a 3% royalty on future net sales, raised the funds to support global pivotal trials. The financing round was co-led by Novo Holdings, SR One, and Catalys Pacific, with participation from a broad syndicate of investors [1].
Urica Therapeutics retains an equity position in Crystalys and is entitled to a 3% royalty on future net sales of dotinurad. This strategic move by Urica is expected to enhance value for its parent company, Fortress Biotech, which holds a majority stake in Urica. The successful Series A financing by Crystalys is a strong endorsement of dotinurad's potential and supports the advancement of its clinical trials [1].
Fortress Biotech, the majority owner of Urica, has a strategic position in the biotechnology sector. Recently, Fortress achieved key milestones, including the acquisition of its subsidiary Checkpoint Therapeutics by Sun Pharma, which delivered approximately $28 million upfront [1]. Fortress' model focuses on leveraging its significant biopharmaceutical industry expertise and network to expand and advance its portfolio of product opportunities.
The significant reliance on external funding through a Series A financing round raises concerns about Urica's own financial stability and resource allocation for the development of its other assets. Forward-looking statements indicate multiple risks and uncertainties surrounding regulatory approval and commercialization, which could severely impact Urica's future earnings and stock price [1].

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