ETHZilla (180 Life Sciences) Shifts to Ethereum Treasury Strategy

ETHZILLA, formerly 180 Life Sciences, has pivoted its strategy to focus on an Ethereum treasury strategy. The bioscience drug research and drug discovery company is now entering the crypto market, abandoning its previous business operations. ETHZILLA has changed its name to reflect its new direction and is expected to provide further updates on its new strategy.

In a significant strategic shift, ETHZilla, formerly known as 180 Life Sciences, has announced its pivot to focus on an Ethereum treasury strategy. This move marks a dramatic change in the company's business direction, as it transitions from bioscience drug research and drug discovery to the crypto market. The company has rebranded and is expected to provide further updates on its new strategy in the coming months.

Rebranding and Strategic Shift

ETHZilla has disclosed that it holds 82,186 ETH, acquired at an average cost of approximately $349 million, and has allocated over $350 million from a private investment in public equity (PIPE) deal and $156 million in convertible notes to expand its Ethereum holdings [1]. The company aims to leverage Ethereum’s dual role as a capital-efficient asset and a store of value, differentiating itself from traditional yield-generating approaches [3].

The strategic shift has been backed by notable investors. Peter Thiel’s Founders Fund has acquired a 7.5% stake in ETHZilla, boosting investor confidence and underscoring the growing institutional interest in the asset class [7]. The firm’s stock has surged between 72% and 75% following the announcement, highlighting strong investor sentiment toward crypto-backed equities [2][4].

Market Impact and Analyst Views

The announcement has had a significant impact on the market. On Aug. 13, 2025, 180 Life Sciences surged 4.49% with a trading volume of $1.24 billion, ranking 67th in market activity. The company’s year-to-date gains now exceed 500% despite initial volatility [2]. However, analysts note that while Ethereum’s price has risen by 72.26% over the past 90 days, the asset’s performance could face headwinds amid evolving regulatory scrutiny and market uncertainty [2].

Comparisons and Future Prospects

ETHZilla’s approach mirrors that of MicroStrategy, which pioneered corporate Bitcoin holdings. The company’s rebranding and capital reallocation highlight the growing intersection of traditional finance and blockchain innovation. However, as more firms explore crypto treasuries, the need for clear regulatory frameworks and transparent data disclosure becomes increasingly critical [5].

ETHZilla’s long-term strategy hinges on executing a disciplined, opportunity-driven Ethereum accumulation model. While it faces inherent risks, including price volatility and regulatory ambiguity, the firm appears confident in its ability to capitalize on Ethereum’s network growth and utility. The partnership with Electric Capital, combined with institutional backing, positions ETHZilla to navigate the crypto landscape with a structured and strategic approach [3][8].

Conclusion

ETHZilla’s pivot to an Ethereum treasury strategy represents a significant shift in the company’s business focus. While the move has been met with strong investor sentiment and notable market activity, it also highlights the risks associated with cryptocurrency investments. As the company continues to provide updates on its new strategy, investors and financial professionals will be closely watching its progress in the crypto market.

References:
[1] https://www.ainvest.com/news/ethereum-news-today-ethzilla-surges-72-rebranding-ethereum-backed-strategy-2508/
[2] https://www.ainvest.com/news/180-life-sciences-surges-4-49-1-24-billion-volume-ranking-67th-ethzilla-rebrand-aligns-trump-crypto-policies-2508/