Esperion Therapeutics Gets Boost from Acquisition Rumors Amid Earnings Release

Tuesday, Jul 29, 2025 9:36 am ET2min read
ESPR--

Esperion Therapeutics (ESPR) surged 5.3% to $1.59, extending its winning streak to five days, amid reports of a potential $900 million acquisition by Japanese pharmaceutical firm Otsuka. The companies are set to meet in August to discuss a deal. ESPR is scheduled to release its Q2 earnings on August 5.

Esperion Therapeutics (ESPR) experienced a significant boost in its stock price, surging 5.3% to $1.59, extending its winning streak to five consecutive days. This upward trend was driven by reports that Japanese pharmaceutical giant Otsuka is in talks to acquire Esperion Therapeutics in a deal potentially valued at $900 million. The two companies are set to meet in August to discuss the acquisition further.

The rumored acquisition comes amidst a backdrop of positive earnings expectations. Esperion Therapeutics is scheduled to release its Q2 earnings on August 5. The company's stock has been on a roll, with the recent speculation adding to its appeal for investors. Esperion Therapeutics has been performing well, with its U.S. business expected to reach profitability by early 2026 and net income of $170 million by 2028 [1].

Otsuka's interest in Esperion Therapeutics is driven by several strategic considerations. The Japanese company is already committed to milestone payments totaling $130 million for the commercial launch of Nexletol® and Nexlizet® in Japan. An acquisition would convert this liability into equity value and simplify long-term economics. Additionally, Esperion Therapeutics stands to receive 25% royalties on Daiichi Sankyo Europe's upcoming triple-combo pill, projected to generate €1 billion in annual sales [1].

The potential acquisition also aligns with Otsuka's operational synergy goals. Esperion Therapeutics' U.S. sales infrastructure could integrate efficiently with Otsuka's existing operations, while the DSE manufacturing transition would resolve a key cost pressure, removing over $30 million in COGS burden annually [1].

The acquisition is not without risks. The company's CEO, Sheldon Koenig, may soon step down due to personal or family health matters, which could present an opportune moment for Otsuka to engage quietly before a formal search process begins. However, the acquisition could also face regulatory hurdles, particularly given the limited overlap in the cardiovascular space and Otsuka's U.S. footprint [1].

Esperion Therapeutics' stock has seen a decline in short interest in June, indicating a positive shift in investor sentiment. As of June 30, 12.35% of the company's shares were sold short, down from 12.45% in May [4]. This trend suggests that investors are increasingly bullish on the company's prospects, both in the absence of a formal acquisition and in light of the potential deal with Otsuka.

Esperion Therapeutics' stock price volatility, driven by the acquisition rumors, underscores the potential impact of strategic partnerships and acquisitions on the biotech sector. Investors should closely monitor the company's earnings release and the progress of the acquisition talks to gauge the potential impact on Esperion Therapeutics' stock price.

References:
[1] https://cafepharma.com/boards/threads/rumors-leaked-otsuka-900-1-1-billion-offer-for-esperion-therapeutics.709894/
[2] https://finance.yahoo.com/news/esperion-therapeutics-espr-gets-boost-133442244.html
[3] https://seekingalpha.com/news/4471632-esperion-therapeutics-soars-amid-vague-takeover-speculation
[4] https://www.marketbeat.com/stocks/NASDAQ/ESPR/short-interest/

Esperion Therapeutics Gets Boost from Acquisition Rumors Amid Earnings Release

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