EscharEx Demonstrates Strong Link Between Wound Bed Preparation and Wound Closure in Venous Leg Ulcers

MediWound announced new EscharEx Phase II data showing a strong link between wound bed preparation and wound closure in venous leg ulcers. Post hoc analysis published in Advances in Wound Care highlights the importance of wound bed preparation in the healing process. Data demonstrates a strong correlation between wound bed preparation and wound closure, with wounds that achieved preparation being 4.1 times more likely to close. Early achievement of wound bed preparation was associated with a significantly increased likelihood of healing.

MediWound Ltd. (Nasdaq: MDWD) recently published post hoc analysis in the journal Advances in Wound Care, demonstrating a significant correlation between wound bed preparation (WBP) and wound closure in venous leg ulcers (VLUs). The study, which analyzed data from 119 VLU patients, found that wounds achieving WBP were 4.1 times more likely to close compared to those that did not (p = 0.0004). Notably, wounds failing to achieve WBP had a 90% probability of not healing [1].

The study also revealed that early WBP achievement (within 14 days) was associated with a 2.4x higher healing rate. The data underscores the critical role of WBP in the healing process, validating what wound care specialists have long theorized: proper debridement and granulation tissue development are rate-limiting steps in chronic wound healing [1].

EscharEx®, MediWound's bromelain-based enzymatic therapy, showed potential in accelerating WBP and improving healing outcomes. The study validates EscharEx's therapeutic approach, strengthening its clinical positioning in the chronic wound care market [1].

The findings reinforce the clinical importance of complete debridement and timely full granulation tissue coverage in facilitating wound closure. This validation of EscharEx's therapeutic approach strengthens its clinical positioning in the chronic wound care market, where effective debridement solutions that can accelerate the preparation phase represent a significant unmet need [1].

References:
[1] https://www.stocktitan.net/news/MDWD/medi-wound-announces-new-eschar-ex-phase-ii-data-demonstrating-lis6gh1wiiv1.html