EliseAI's AI Plays Fixer for $600B Healthcare Mess and Housing Woes

EliseAI has secured $250 million in a Series E funding round led by Andreessen Horowitz (a16z), with additional participation from Bessemer Venture Partners and existing investors Sapphire Ventures and Navitas Capital. The round values the enterprise AI startup at over $2.2 billion, doubling its valuation from approximately a year ago. This capital infusion is intended to accelerate product innovation, expand the workforce, and scale operations in the healthcare and housing industries [1][2].

Since its $75 million Series D in August 2024, EliseAI has more than doubled its full-time workforce, growing from 150 to over 300 employees. The company also surpassed $100 million in Annual Recurring Revenue (ARR) earlier this year. The funding will support the hiring of talent across engineering, customer experience, sales and marketing, and strategy, with a focus on expanding its presence in New York, San Francisco, Boston, and Chicago [1].

EliseAI is leveraging its AI technology to streamline operations in two of the most complex and costly sectors: healthcare and housing. In healthcare, the company is addressing administrative inefficiencies, particularly in front-desk and call center operations, where annual costs in the U.S. exceed $600 billion. Its platform automates tasks such as scheduling, prior authorizations, and patient support, improving efficiency and reducing wait times. One customer, Women’s Health CT – Obstetrics & Gynecology, reported significant improvements in workflow and patient experience after implementing EliseAI’s solutions [1].

In the housing sector, EliseAI has developed a range of AI-powered tools to manage rising operational costs and high turnover rates. Products such as AI-Guided Tours, Lease Audits, and the Maintenance App help property managers streamline operations and improve resident experiences. The company supports over 600 property owners and operators, including 75% of NMHC’s Top 50 Operators, and currently powers 10% of the U.S. apartment market [1].

The investment aligns with growing interest in vertical AI solutions that deliver industry-specific automation rather than generalized models. EliseAI’s approach, which integrates with existing systems like electronic health records, allows it to handle complex customer requests, from initial inquiry to resolution, including coordination with vendors and compliance checks. This deep integration is a key differentiator in a market that is shifting from theoretical AI discussions to practical applications [2].

The firm’s expansion into healthcare came in 2022, following its initial focus on housing since 2017. It has since concentrated on outpatient specialties such as dermatology and women’s health. The integration of generative AI has further enhanced its ability to manage nuanced workflows and customer inquiries. EliseAI’s success in both sectors highlights the potential of AI to transform traditionally labor-intensive industries through automation and efficiency [2].

Source: [1] EliseAI Raises $250M Series E (https://www.eliseai.com/blog/eliseai-raises-250m-series-e) [2] EliseAI raises $250 million in a16z-led round to expand in ... (https://www.reuters.com/business/healthcare-pharmaceuticals/eliseai-raises-250-million-a16z-led-round-expand-healthcare-2025-08-20/)