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On August 20, 2025,
(LLY) closed with a 0.32% gain, trading at $703.67. The stock saw a daily trading volume of $2.89 billion, a 31.27% decline from the prior day, ranking 20th in market activity. A leadership transition in its neuroscience division is poised to influence investor sentiment, as Anne White, who led the unit since 2021, announced her retirement in December after three decades at the company. White’s tenure included pivotal roles in regulatory approvals and launches of Alzheimer’s drug Kisunla, as well as strategic oncology acquisitions. Her departure prompts a search for a successor, with internal and external candidates under consideration.White’s retirement follows her leadership in advancing Kisunla, a drug designed to slow Alzheimer’s progression, which marked a significant milestone for
after years of unmet expectations. The company has also streamlined Kisunla’s dosing to mitigate a severe side effect, ARIA, and is developing another Alzheimer’s candidate, remternetug, in Phase 3 trials. Lilly’s neuroscience pipeline includes gene therapies for Parkinson’s and other neurodegenerative conditions, alongside pain treatments acquired through recent partnerships. Analysts note that while Kisunla’s sales remain modest, its regulatory success has positioned the division for long-term growth.The strategy of buying the top 500 stocks by daily trading volume and holding them for one day from 2022 to now delivered moderate returns. The 1-day return was 0.98%, with a total return of 31.52% over 365 days. This indicates the strategy captured some short-term momentum but also reflected market volatility and potential timing risks.

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