Eli Lilly's diabetes medication, Mounjaro, has shown cardiovascular benefits comparable to traditional heart medications, positioning it to become physicians' top choice for a massive patient population. This breakthrough could expand Mounjaro's prescribing potential, accelerate the company's momentum, and lead to potential regulatory approval and favorable insurance coverage by 2026. As a leading pharmaceutical firm with a strong presence in diabetes treatments, Eli Lilly's stock could see significant growth with this development.
Eli Lilly's diabetes medication, Mounjaro (tirzepatide), has shown significant cardiovascular benefits comparable to traditional heart medications, positioning it as a potential top choice for physicians treating a massive patient population. The results of the SURPASS-CVOT trial, a head-to-head comparison of Mounjaro and Trulicity (dulaglutide), indicate that Mounjaro achieved non-inferiority in reducing major adverse cardiovascular events (MACE-3), including cardiovascular death, heart attack, and stroke [1]. This breakthrough could expand Mounjaro's prescribing potential, accelerate Eli Lilly's momentum, and lead to potential regulatory approval and favorable insurance coverage by 2026.
The SURPASS-CVOT trial, which enrolled over 13,000 participants across 30 countries and lasted more than four and a half years, found that Mounjaro reduced the risk of MACE-3 by 8% compared to Trulicity [1]. Additionally, Mounjaro demonstrated a 16% lower rate of all-cause death and provided greater reductions in blood sugar levels, body weight, and slowed kidney function decline compared to Trulicity [2]. The safety profiles of both drugs were consistent with previous studies, with mostly mild gastrointestinal side effects reported [1].
The trial results reinforce Mounjaro’s established safety and treatment properties, and the company plans to present the findings at the European Association for the Study of Diabetes annual meeting in September 2025 [1]. The results will also be published in a peer-reviewed journal and submitted to global regulatory authorities by the end of the year [1].
As a leading pharmaceutical firm with a strong presence in diabetes treatments, Eli Lilly's stock could see significant growth with this development. The trial results suggest that Mounjaro could expand its market share in the diabetes treatment landscape, potentially leading to increased revenue and profitability for the company.
References:
[1] https://www.pharmexec.com/view/lilly-mounjaro-cardiovascular-protection-trial
[2] https://www.financialexpress.com/business/healthcare-landmark-head-to-head-trial-reveals-cardiovascular-benefits-of-eli-lillys-diabetes-drug-mounjaro-3932977/
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