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Eli Lilly and AstraZeneca's Phase 3 Study on KRAS G12C-Mutant NSCLC: A Promising Update for Cancer Treatment Options.
ByAinvest
Saturday, Jul 26, 2025 3:38 am ET1min read
Eli Lilly and AstraZeneca are conducting a Phase 3 clinical study to evaluate the effectiveness of olomorasib combined with standard immunotherapies in treating KRAS G12C-mutant non-small cell lung cancer. The study aims to improve outcomes for patients with resected or unresectable NSCLC. Recruitment is ongoing, with further details available on the ClinicalTrials portal. Positive results could enhance the market positions of Eli Lilly and AstraZeneca in the oncology sector.
Eli Lilly and Company (LLY) and AstraZeneca (AZN) are conducting a pivotal Phase 3 clinical trial to evaluate the effectiveness of olomorasib in combination with standard immunotherapies for treating KRAS G12C-mutant non-small cell lung cancer (NSCLC). The study, titled "SUNRAY-02," aims to improve outcomes for patients with resected or unresectable NSCLC by testing olomorasib, an oral drug, in combination with pembrolizumab and durvalumab, both administered intravenously.The study began on March 27, 2025, with recruitment ongoing and the last update submitted on July 22, 2025. The randomized, double-blind, placebo-controlled design follows a parallel intervention model, ensuring rigorous testing of the drug combinations against placebo. The primary purpose of the study is to establish the efficacy of the new drug combinations in treating KRAS G12C-mutant NSCLC.
The potential success of this trial could significantly impact the stock performance of Eli Lilly and AstraZeneca. Positive results could enhance their market positions in the oncology sector, positioning them favorably against competitors. Investors should monitor the study's progress, as positive outcomes could shift market dynamics in the competitive field of cancer treatment.
Further details about the study are available on the ClinicalTrials portal.
References:
[1] https://www.theglobeandmail.com/investing/markets/stocks/LLY/pressreleases/33622798/eli-lilly-and-astrazenecas-promising-phase-3-trial-for-kras-g12c-mutant-nsclc/
[2] https://www.tipranks.com/news/company-announcements/eli-lilly-and-astrazenecas-promising-phase-3-study-on-kras-g12c-mutant-nsclc-2
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