Elanco Animal Health to Replace Sarepta Therapeutics in S&P MidCap 400; Sarepta Therapeutics to Replace Brookline Bancorp in S&P SmallCap 600.

Wednesday, Aug 27, 2025 1:21 am ET1min read

Elanco Animal Health will replace Sarepta Therapeutics in the S&P MidCap 400, and Sarepta Therapeutics will replace Brookline Bancorp in the S&P SmallCap 600, effective before the opening of trading on Tuesday, September 2.

Elanco Animal Health Inc. (NYSE: ELAN) will replace Sarepta Therapeutics Inc. (NASDAQ: SRPT) in the S&P MidCap 400, and Sarepta Therapeutics will replace Brookline Bancorp Inc. (NASDAQ: BRKL) in the S&P SmallCap 600, effective before the opening of trading on Tuesday, September 2. The changes are part of a broader rebalancing of the indices, reflecting the ongoing evolution of the financial markets.

Elanco Animal Health, a leading animal health company, is set to enter the S&P MidCap 400, a benchmark index for mid-cap stocks. The company's inclusion signals confidence in its financial performance and growth prospects. Meanwhile, Sarepta Therapeutics, a biopharmaceutical company, will join the S&P SmallCap 600, a smaller-cap index. This move underscores Sarepta's potential for growth and innovation in the biotechnology sector.

The changes come amid a series of corporate actions. Berkshire Hills Bancorp Inc. (XNYS: BHLB), a constituent of the S&P SmallCap 600, is acquiring Brookline Bancorp Inc. in a deal expected to be completed soon. Post-merger, Berkshire Hills Bancorp will remain in the S&P SmallCap 600 with a name and ticker change to Beacon Financial Corp. (NYSE: BBT).

These index changes are part of a broader strategy by S&P Dow Jones Indices to ensure that their benchmarks accurately reflect the current financial landscape. The S&P MidCap 400 and S&P SmallCap 600 are widely followed indices, and their composition can influence investment decisions.

For more information about S&P Dow Jones Indices and the changes, please visit [www.spdji.com](http://www.spdji.com).

References:
[1] https://www.nasdaq.com/press-release/elanco-animal-health-set-join-sp-midcap-400-sarepta-therapeutics-join-sp-smallcap-600
[2] https://www.morningstar.com/news/pr-newswire/20250826ny59846/elanco-animal-health-set-to-join-sp-midcap-400-sarepta-therapeutics-to-join-sp-smallcap-600
[3] https://seekingalpha.com/news/4489372-elanco-animal-health-set-to-join-sp-midcap-400-sarepta-to-join-sp-smallcap-600

Elanco Animal Health to Replace Sarepta Therapeutics in S&P MidCap 400; Sarepta Therapeutics to Replace Brookline Bancorp in S&P SmallCap 600.

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