Dynavax Technologies 2025 Q1 Earnings Misses Targets as Net Loss Widens 1002%
Wednesday, May 7, 2025 6:34 am ET
Revenue
Dynavax Technologies experienced a notable revenue increase of 35.8% in 2025 Q1, totaling $64.96 million, surpassing the $47.84 million recorded in Q1 2024. The company achieved $64.96 million in net product revenue, complemented by $3.21 million from other revenue sources, culminating in total revenues of $68.16 million.
Earnings/Net Income
Dynavax's fiscal 2025 Q1 results revealed a substantial increase in net loss, escalating to $96.10 million from $8.72 million in the prior year, and translating to a loss of $0.77 per share compared to $0.07. The widening loss signals significant financial challenges for the quarter.
Price Action
The stock price of dynavax technologies edged down by 1.71% on the latest trading day, has dropped 5.45% over the most recent full trading week, and has plummeted 15.02% month-to-date.
Post-Earnings Price Action Review
Over the past five years, Dynavax Technologies has demonstrated a profitable strategy of buying shares after a revenue drop quarter-over-quarter and holding them for 30 days. This method has yielded an impressive 183.88% return, outperforming the benchmark by 100.76%. Despite experiencing a maximum drawdown of -25.70%, the strategy has shown resilience and potential as a robust investment approach in dynamic markets. Its consistent success indicates that this strategy could be a valuable consideration for investors looking to navigate the fluctuating biopharmaceutical sector with Dynavax.
CEO Commentary
Ryan Spencer, CEO, expressed optimism about Dynavax's strong start to 2025, highlighting the record first-quarter net revenue of $65 million for HEPLISAV-B, marking a 36% year-over-year increase. He emphasized the company's focus on advancing its development pipeline, noting significant clinical trial milestones for shingles and plague vaccine programs. Spencer sees significant opportunity for a differentiated shingles vaccine in a multibillion-dollar global market and remains confident in leveraging their CpG-1018 adjuvant technology for lower-risk development pathways.
Guidance
Dynavax expects HEPLISAV-B net product sales to be between $305 million and $325 million for 2025, reflecting a 17% year-over-year growth at the midpoint. The CEO reiterated expectations for adjusted EBITDA to reach at least $75 million, showing strong growth potential. Spencer conveyed confidence in achieving the top half of the revenue guidance range following a robust start to the year.
Additional News
Dynavax Technologies has been active in improving its financial structure and shareholder returns. In March 2025, the company completed a convertible debt refinancing, extending the maturity of most existing debt and reducing dilution to its capital structure. This strategic move aims to lower overall capital costs and enhance financial stability. Additionally, Dynavax has actively pursued its $200 million share repurchase program, having already repurchased $172 million worth of common stock by May 5, 2025. This initiative reflects the company's commitment to returning value to shareholders amid recent stock price volatility.

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