CytomX Therapeutics: EpCAM's Reappearance Requires Validation
ByAinvest
Wednesday, Dec 24, 2025 7:03 am ET1min read
CTMX--
CytomX Therapeutics has reported preliminary data for its EpCAM-targeted, topo-1 Probody-ADC, CX-2051, in metastatic colorectal cancer. The company is evaluating 2051 in mCRC. Historically, ADCs have had a limited response rate in mCRC patients. Despite the recent positive data, CytomX Therapeutics' rating has been downgraded due to the need to prove that EpCAM holds promise in this indication.
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