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CureVac (CVAC) Q3 Earnings call transcript Nov 12, 2024

Daily EarningsTuesday, Nov 12, 2024 7:14 pm ET
2min read

In the latest financial results and business update conference call, CureVac presented a solid performance in the third quarter of 2024, showcasing a robust financial position and strategic advancements in their oncology and infectious diseases pipelines. This report provides a comprehensive analysis of the earnings call, focusing on key themes, trends, and investor questions.

Financial Highlights:CureVac reported a strong financial position with a cash balance of EUR 550.9 million at the end of Q3 2024, providing a solid financial runway into 2028. The company's cash position was boosted by a EUR 400 million upfront payment from the GSK licensing agreement, which positively impacted the cash position and revenues. Operating profit for the quarter reached EUR 368.4 million, marking a significant improvement compared to the previous year's operating loss.

Strategic Transformation and Pipeline Progress:CureVac is undergoing a strategic transformation, including a 30% reduction in workforce by the end of 2024, which is expected to contribute to substantial cost savings and operational efficiency improvements starting in 2025. The company is focused on high-value opportunities in oncology and infectious diseases, with a clear focus on innovation and R&D activities.

In oncology, CureVac is advancing off-the-shelf and personalized cancer vaccines, including a Phase I study in patients with resected glioblastoma, which has shown promising early results. The company is planning new trials in 2025 and 2026, aiming to accelerate its path to the clinic. In infectious diseases, CureVac is working on a UPEC vaccine for urinary tract infections, which has the potential to deliver a best-in-class solution for this common infection. Additionally, CureVac's partner, GSK, is advancing a seasonal influenza vaccine into Phase III next year and is about to initiate a combined Phase I/2 study for a COVID-19 influenza combination vaccine.

Patent Litigation:CureVac provided an update on patent litigation, with a key event scheduled for March 2025 in the U.S. The company is preparing for this event and expects further rulings from the European patent office and the regional court in Dusseldorf in the second and third quarters of 2025. The litigation is expected to continue throughout 2025 and potentially into 2026 on a case-by-case basis in Europe.

Investor Questions:During the Q&A session, investors raised questions about business opportunities outside of CureVac's core expertise, the progress of the flu-COVID combination vaccine, and the selection of lung cancer as a new indication. CureVac's executives provided insightful responses, highlighting their focus on oncology and infectious diseases and their ongoing efforts to strengthen their portfolio in these areas. They also shared details on the promising progress of their flu-COVID combination vaccine program and the scientific rationale behind selecting lung cancer as a new indication.

Conclusion:CureVac's Q3 2024 financial results and business update underscore the company's strong financial position, strategic focus, and pipeline progress in oncology and infectious diseases. With a clear path forward and strategic partnerships, CureVac is well-positioned to tackle major health challenges and continue its growth trajectory.

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