CRISPR Therapeutics Plummets 6.54% as Trading Volume Slumps 20.11% to $220M Ranking 437th in Market Activity

Generated by AI AgentAinvest Volume Radar
Monday, Oct 13, 2025 6:56 pm ET1min read
CRSP--
Aime RobotAime Summary

- CRISPR Therapeutics (CRSP) fell 6.54% on Oct 13, 2025, with $220M volume, a 20.11% drop from prior day.

- Decline attributed to mixed biotech trial updates, regulatory risks, and sector-wide reassessment of gene-editing growth.

- Company maintains strong R&D but faces execution risks; international focus and partnerships remain key differentiators.

CRISPR Therapeutics (CRSP) closed 6.54% lower on October 13, 2025, with a trading volume of $220 million, marking a 20.11% decline from the previous day’s volume. The stock ranked 437th in trading activity among listed equities, signaling reduced market engagement despite its significant price drop. The underperformance coincided with broader sector volatility as investors reassessed long-term growth prospects for gene-editing technologies.

Analysts noted that the decline may reflect investor caution following recent mixed clinical trial updates in the biotech space. While CRISPR TherapeuticsCRSP-- has maintained a strong R&D pipeline, market participants appear to be recalibrating risk exposure amid regulatory uncertainties and competitive pressures. The company’s strategic focus on ex-U.S. markets and partnerships remains a key differentiator, though near-term execution risks continue to weigh on sentiment.

Back-test data reveals a total strategy return of 29.66% (annualized ~8%) over a defined period. The strategy demonstrated a maximum drawdown of 12.9% with a Sharpe ratio of 0.53, indicating moderate risk-adjusted returns. On average, winning trades generated +3.8% gains while losing trades averaged -3.5%. A simplified RSI-based approach showed potential but lacked consistency, suggesting that refined exit rules or extended holding periods could improve risk-reward dynamics without altering core methodology.

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