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Centene Corporation’s subsidiary Arizona Complete Health has secured a pivotal Medicaid contract to manage long-term care services for nearly 26,000 Arizonans, marking a significant expansion of its presence in one of the U.S.’s fastest-growing healthcare markets. The settlement agreement with the Arizona Health Care Cost Containment System (AHCCCS) resolves prior disputes and paves the way for statewide coverage under the Arizona Long Term Care System (ALTCS) program, effective October 1, 2025. This move positions Centene to capitalize on demand for integrated care while navigating mounting regulatory and financial pressures.

The three-year contract with an optional three-year extension allows Centene to serve as the primary provider for the ALTCS-Elderly and Physically Disabled (ALTCS-EPD) program. The agreement covers physical and behavioral healthcare, pharmacy benefits, and home- and community-based services aimed at enabling independent living. With a potential six-year term, this deal reinforces Centene’s position as Arizona’s largest Medicaid plan, serving over 400,000 residents since 2006.
The rollout aligns with Centene’s strategy to expand into high-need segments of Medicaid, particularly long-term care—a sector projected to grow as aging populations and chronic conditions drive demand. CEO Sarah M. London emphasized the “member-first” focus of the agreement, highlighting efforts to streamline transitions and improve health outcomes through coordinated care.
The contract arrives amid heightened scrutiny of Centene’s Medicaid profitability. In Q4 2024, Centene reported a 93.4% medical loss ratio (MLR) for Medicaid, up from 93.1% in Q3, signaling escalating medical costs due to the “Medicaid unwinding” process. This federal mandate required states to reassess eligibility post-pandemic, leaving sicker, costlier enrollees in the program.
To offset these pressures, Centene has secured average Medicaid rate increases of 3–4% for 2025, with some states approving a 4.5% boost for early 2025 coverage. CEO London noted progress toward “equilibrium,” where rate hikes align with rising acuity. However, delays in securing retroactive adjustments through 2024 contributed to the elevated MLR, underscoring the timing risks inherent in state-level negotiations.
While the Arizona contract offers growth potential, Centene faces persistent risks. The cybersecurity settlement with the U.S. Department of Justice—where Centene paid $11.25 million to resolve False Claims Act violations linked to its TRICARE subsidiary—highlights the regulatory risks of federal contracting. Though this issue stems from a legacy subsidiary (Health Net Federal Services), it underscores vulnerabilities in compliance and cybersecurity governance.
Additionally, the Medicaid unwinding’s lingering effects and evolving state policies pose operational challenges. For instance, Arizona’s requirement to notify members of plan assignments by mid-2025 demands flawless execution to avoid disruptions. Meanwhile, Centene’s reliance on Medicaid (accounting for ~60% of revenue) leaves it vulnerable to payment delays and policy shifts, such as changes to eligibility criteria or funding levels.
Centene’s foray into Affordable Care Act (ACA) markets offers a critical counterweight. With 5 million effectuated ACA members in 2025—up from 4.8 million in 2024—the division generates lower MLRs (89.6% in Q4 2024) and federal subsidies, contributing $3.3 billion in annual profits. However, ACA enrollment may peak in early 2025 due to stricter program integrity measures, such as agent-of-record locks and tax reporting requirements, which could slow new enrollments.
Centene’s Arizona contract is a calculated move to deepen its Medicaid footprint in a state with a growing population and rising healthcare needs. The deal’s six-year potential aligns with Centene’s long-term vision, but success hinges on executing three key factors:
With Medicaid enrollment stabilizing post-unwinding and long-term care demand surging, Centene’s Arizona expansion positions it to capture a growing market. However, investors must weigh this opportunity against lingering financial pressures and regulatory uncertainties. For now, the stock—up 18% year-to-date—reflects optimism, but sustained outperformance will depend on Centene’s ability to turn contractual wins into margin stability.
In a sector where 1% swings in MLR can significantly impact profits, Centene’s path to equilibrium remains narrow. Yet, with its scale and state partnerships, the company is well-positioned—if it can navigate these challenges—to solidify its role as a Medicaid leader in an evolving healthcare landscape.
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