Cencora Surges to $440M Volume Ranking 282nd in U.S. Trading Amid Healthcare Sector Shifts
, , . . equities, indicating heightened market engagement. Recent developments suggest renewed institutional interest in the healthcare supply chain services provider, driven by strategic positioning in a sector experiencing regulatory and operational shifts.
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To run this back-test accurately I need to clarify a few practical details and assumptions: 1. Stock universe • Should we use all U.S. common stocks listed on NYSE + NASDAQ + AMEX, or a different universe? 2. Ranking frequency and holding logic • The usual interpretation is: – Every trading day at the close we rank that day’s universe by trading volume. – Buy (equal-weight) the top-500 names at that same close. – Exit those positions at the next day’s close (i.e., a 1-day holding period). • Please confirm this “close-to-close” convention (or let me know if you prefer open-to-close or some other variant). 3. Weighting scheme • Equal-weighted across the 500 names (default), or volume-weighted / market-cap-weighted? 4. Cash & transaction assumptions • Ignore transaction costs and slippage (default), or should we include an estimate? Once I have these points confirmed I can generate the retrieval plan, pull the daily volume data, build the daily portfolios and run the strategy back-test from 2022-01-01 through today.

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