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Cencora (COR) reported Q4 2025 earnings that fell far below expectations, with a net loss of $333.07 million compared to a $7.47 million profit in 2024 Q4. The results prompted a strategic review of non-core businesses and a $724 million goodwill impairment. Management raised long-term adjusted operating income growth guidance to 6-9% and adjusted EPS growth to 9-13%, signaling confidence in its strategic investments.
U.S. , . A minor intersegment adjustment of $-4.93 million offset the total, , .

, a 4561.2% deterioration from a $0.02 profit in 2024 Q4. The net loss of $333.07 million reflects persistent margin pressures and a $724 million goodwill impairment. The results underscore significant challenges in maintaining profitability despite revenue growth.
, , . The strategy of buying shares on earnings beats and holding for 30 days yielded a 17.8% CAGR over three years, outperforming the market’s 11.2%.
. However, . Analysts remain divided, with some emphasizing long-term growth potential in digital infrastructure and others cautioning about margin pressures. , reflecting mixed sentiment.
, , . , . Institutional investors, including Advisors Preferred LLC and Freestone Capital, increased holdings, .
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