Cardiol Therapeutics Inc. rose 7.48% in premarket trading, driven by the announcement of topline results from the ARCHER trial, which showed a notable improvement in the primary endpoint of left ventricular (LV) extracellular volume (ECV) favoring CardiolRx™ over placebo. The reduction in ECV was associated with improvements across multiple pre-specified cardiac magnetic resonance imaging (CMR) endpoints, including a significant reduction in LV mass. These results provide compelling clinical proof of concept for CardiolRx™ and strongly support advancing its clinical development in cardiomyopathies, heart failure, and myocarditis.
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