Cardinal Health's $1.03 Billion Trading Volume Surge Propels 104th Rank as Strategic Shifts Unfold

On October 3, 2025, Cardinal Health (CAH) saw a trading volume of $1.03 billion, representing a 104.86% increase from the previous day. The stock closed 2.52% lower, ranking 104th in trading volume among listed companies that day.

Recent developments highlight a strategic shift in Cardinal Health’s operations. The company announced a partnership with a leading pharmaceutical logistics provider to streamline its supply chain. This collaboration aims to reduce distribution costs and enhance operational efficiency, potentially stabilizing long-term earnings growth. Analysts noted the move could address persistent margin pressures in the healthcare sector.

Investor sentiment was further influenced by Cardinal Health’s decision to divest its non-core specialty pharmacy segment. The transaction, expected to close by year-end, is projected to generate $800 million in proceeds. While the near-term impact on revenue remains neutral, the move aligns with a broader strategy to focus on high-margin core services, including hospital pharmacy solutions and medical supply distribution.

Market participants are also monitoring Cardinal Health’s response to regulatory changes in Medicaid reimbursement rates. The company disclosed plans to implement cost-saving measures across its clinical services division, which accounts for 30% of total revenue. These adjustments are seen as defensive tactics to mitigate the impact of policy-driven margin compression in the coming quarters.

I understand the idea: each trading day from 2022-01-01 to today, form a basket consisting of the 500 stocks with the highest dollar trading volume, buy them at that day’s close (or open), and liquidate at the next day’s close (or open). The result you want is the aggregate portfolio return curve and risk statistics for that daily-rebalanced, equally-weighted 500-stock basket. At the moment, the automated back-test engine I can call from here works on one security at a time (or on a list of event dates for one security). It does not yet support constructing and rebalancing a multi-stock portfolio on the fly. To proceed, we have two practical options: 1. Narrow the request to a single security or an index (e.g., SPY, QQQ, etc.) and back-test a simple rule on that ticker. 2. Export a full list of daily “buy” universes (the 500 tickers per day) so you can run the portfolio back-test offline. Please let me know which direction (or another) you’d like to take, and I’ll move forward accordingly.