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In the Stock Gainers Section:
GCL Global (GCL) experienced a significant rise of 145.97%. The company's stock surged following the completion of a business merger with RF Acquisition Corp. GCL is set to begin trading on the Nasdaq under the ticker "GCL" and announced a bell-ringing ceremony to commemorate its listing.
GeneDx Holdings (WGS) saw an increase of 47.69%. The company’s shares skyrocketed after its fourth-quarter earnings exceeded market expectations.
Allogene Therapeutics (ALLO) climbed by 39.22% and has been on a two-day upward streak, marking a 101.42% increase over this period. A favorable buy rating was maintained by Baird, boosting investor confidence.
LanzaTech Global (LNZA) advanced 35.19%, continuing a three-day rally, culminating in a 47.64% rise over these days. This surge is a result of a collaboration among Hafner Energy, Lanzajet, and LanzaTech to promote the production of sustainable aviation fuel (SAF) derived from biomass residues.
Solid Biosciences (SLDB) increased by 31.51%, maintaining a four-day upward trend, for a total gain of 60.61%. The company's stock appreciated after announcing positive clinical trial data for its Duchenne muscular dystrophy therapy, SGT-003.
In the Stock Losers Section:
Septerna (SEPN) dropped by 46.99%. The stock plummeted to a new low following the decision to cease a trial.
Cloudastructure (CSAI) decreased by 44.88%, marking its second consecutive day of losses, amounting to a total of 72.13% over these two days. The company's stock fell 12% after filing a prospectus for stock sales.
Critical Metals (CRML) fell by 26.27%, extending a five-day downward trend, culminating in a 56.69% loss over this period. The decline followed the company’s completion of a private placement that raised $22.5 million, which resulted in a 5% drop in share price.
Jeld-wen Holding (JELD) saw a decline of 23.32%. Despite reporting sales of $895.7 million, surpassing the expected $861.74 million, the company's fourth-quarter adjusted earnings per share came in at $(0.10), missing the market's anticipation of $(0.06).
Donnelley Financial Solutions (DFIN) declined by 22.63%, continuing a two-day fall, for a total drop of 23.43%. The company’s shares decreased by over 16%, heading toward its largest percentage drop since February 2023.

Knowing stock market today at a glance

Dec.22 2025

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Dec.22 2025
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