Bristol Myers Squibb: A Hidden Gem in Biotech with 4.6% Yield and Undervalued Growth

Isaac LaneSunday, Jun 1, 2025 4:49 am ET
147min read

Bristol Myers Squibb (BMY) is quietly emerging as one of the most compelling opportunities in the healthcare sector today. With a dividend yield of 4.6%, a forward P/E ratio of , and a robust pipeline of innovative therapies, the company presents a rare blend of income appeal and growth potential. Despite near-term headwinds from patent expirations, BMY's diversified drug portfolio, strong cash flow, and shareholder-friendly capital allocation strategies position it to outperform the S&P 500 in the years ahead.

A Dividend Machine with Room to Grow

BMY's dividend yield of 4.6% (as of May 2025) is among the highest in the biopharma sector, far surpassing the S&P 500's average of 1.8%. While the company's trailing twelve-month (TTM) earnings are negative due to one-time charges and patent-related revenue declines, its operating margin improved to 29.5% in Q1 2025, signaling a turnaround in profitability. Adjusted EBITDA of $5.19 billion (a 35.5% beat to estimates) underscores its ability to generate cash even amid headwinds.

The dividend itself has been stable at $0.62 per share since early 2024, with a 3-year average growth rate of 7.58%, suggesting management prioritizes shareholder returns. A forward-looking perspective reveals that BMY's free cash flow margin, though down to 15.1% in Q1 2025, remains sufficient to fund both dividends and its $5.1 billion R&D budget.

A Diversified Portfolio Anchored by Blockbusters

BMY's revenue is underpinned by a portfolio of $40 billion+ therapies, including:
1. Opdivo (nivolumab): A cornerstone cancer immunotherapy with recent European approvals for multiple solid tumors and non-small cell lung cancer.
2. Eliquis: A leading blood thinner with minimal generic competition in the U.S. through 2034.
3. Revlimid (lenalidomide): A myeloma treatment that remains resilient despite patent expirations, thanks to new indications and geographic expansion.

The European approvals for Opdivo, along with partnerships with companies like Karuna and Mirati Therapeutics, highlight BMY's focus on high-margin, specialty therapies. This diversification reduces reliance on any single product, a critical advantage in an industry rife with generic threats.

A Pipeline Fueling Future Growth

BMY's pipeline is its most compelling long-term asset. Key programs include:
- Relatlimab + Nivolumab: A combination therapy for advanced melanoma, approved in 2023, with potential in other cancers.
- Lifileucel (KTE-C19): A CAR-T cell therapy for multiple myeloma, now commercialized in the U.S. and EU.
- BMS-986175: A next-gen PD-1 inhibitor with broader cancer applications than Opdivo.

The recent European green light for Opdivo's perioperative regimen in lung cancer—a first for the therapy—demonstrates BMY's ability to expand indications and extend drug lifecycles. Management has also prioritized cost discipline, with $1.5 billion in annual savings from its 2023 restructuring plan, freeing capital for R&D and acquisitions.

Navigating Patent Expirations with Strategy

While patent cliffs for Revlimid (U.S. expires 2034) and Eliquis (U.S. expires 2034) pose near-term risks, BMY's strategy to broaden its therapeutic reach mitigates these headwinds. For instance:
- Revlimid's global sales rose 7% in 2024 due to new uses in China and emerging markets.
- Eliquis' U.S. exclusivity is further bolstered by its superiority over warfarin in stroke prevention.

Crucially, BMY's 2025 forward P/E of 7× reflects market skepticism about its ability to navigate these challenges. By contrast, peers like Eli Lilly (LLY, P/E 118×) trade at premiums due to near-term growth, while Johnson & Johnson (JNJ, P/E 10.5×) offers stability but less upside. BMY's valuation leaves room for multiple expansion as its pipeline bears fruit.

Why Act Now?

BMY's stock trades at a 4,728% discount to its 10-year average P/E, a valuation anomaly for a company with $50 billion in annual revenue and $102 billion market cap. The $0.62 dividend is safe, and the upcoming May 1, 2025 dividend offers immediate income.


Historical data reveals that a strategy of buying BMY on its ex-dividend date and holding for 90 days since 2020 would have delivered an average return of 7.91%, though with significant volatility—peaking at a maximum drawdown of -39.78%. The Sharpe ratio of 0.07 underscores the trade-off between reward and risk.

Investors should also note BMY's $2.0 billion revolving credit facility and strong balance sheet, which provide flexibility for strategic acquisitions or buybacks. With adjusted EBITDA margins near 46%, the company can reinvest in high-return projects while maintaining its dividend.

Conclusion: A Rare Blend of Income and Growth

BMY's 4.6% yield, forward P/E of 7×, and $5.19 billion in adjusted EBITDA make it a standout pick for investors seeking both income and growth. While patent expirations are real risks, BMY's pipeline, cost discipline, and geographic expansion strategies position it to outperform peers over the next five years.

For income-focused investors, BMY's dividend provides a 4.6% yield with upside, while its valuation offers a margin of safety. For growth investors, its 15+ late-stage pipeline candidates and leadership in immuno-oncology and hematology promise to drive earnings recovery.

In a market where high yield and growth are increasingly scarce, BMY offers both—and at a price that doesn't yet reflect its potential. This is a stock to buy now, hold for dividends, and watch as its pipeline transforms into real-world revenue.

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