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Maestro, a leading infrastructure provider for
DeFi, has partnered with the DFINITY Foundation to develop an enterprise-grade indexer for the Internet Computer Protocol (ICP) that enhances Bitcoin’s smart contract capabilities. This tool enables real-time validation of Ordinals and Runes data within ICP canisters, offering developers secure and reliable access to Bitcoin’s native protocols. The indexer, funded through a grant from the DFINITY Foundation, supports applications requiring trustless cross-chain interactions, such as instant cross-chain loans and tokenization, without relying on bridges or intermediaries [1].The collaboration builds on ICP’s Chain Fusion technology, which has already enabled successful Bitcoin DeFi projects like Liquidium, Omnity, and Odin.fun. Maestro’s system introduces features like mempool-awareness and protection against blockchain reorganizations, ensuring high performance and secure data delivery [2]. Liquidium, the largest Bitcoin lending protocol, will be the first to adopt the new indexer for its cross-chain loan product, allowing users to lock BTC on Bitcoin’s Layer 1 and borrow USDT on
[3].Maestro’s CEO, Marvin Bertin, emphasized the partnership’s role in solidifying ICP’s leadership in Bitcoin DeFi. By providing developers with direct access to Ordinals and Runes data, the platform expands possibilities for applications combining Bitcoin’s liquidity with ICP’s cross-chain capabilities. This aligns with Maestro’s mission to accelerate the transition to a Bitcoin-based financial system through scalable infrastructure [4].
The open-source nature of the indexer is expected to foster innovation in Bitcoin DeFi. With over 1,000 developers and 200+ applications already using Maestro’s tools, the expansion to ICP ecosystem aims to streamline development of decentralized finance, gaming, and other use cases. DFINITY Foundation’s VP of Growth, Lomesh Dutta, highlighted the project’s potential to drive innovation by eliminating reliance on intermediaries, leveraging Chain Fusion’s unique integration with Bitcoin [5].
Analysts note that while the integration addresses demand for Bitcoin-native DeFi tools, adoption hinges on developer uptake and security consistency with Bitcoin’s design. The system’s real-time mempool monitoring and cross-chain interoperability are critical for enabling complex financial applications like staking and derivatives [6]. Despite these advancements, challenges remain in scaling infrastructure to meet growing demand, requiring ongoing optimization of performance and security [7].
The project underscores the synergy between ICP’s decentralized infrastructure and Bitcoin’s protocol. By embedding validation processes into ICP canisters, Maestro minimizes reliance on centralized services, aligning with Bitcoin’s decentralization principles. This collaboration positions ICP as a scalable platform for Bitcoin DeFi, with Maestro serving as a key enabler for tokenization and decentralized applications [8].
Sources:
[1] [DL News] [https://www.dlnews.com/research/external/maestro-advances-native-ordinals-and-runes-indexer-on-icp-to-power-bitcoin-defi/]
[2] [CryptoPotato] [https://cryptopotato.com/bitcoin-defi-empowered-by-maestro-and-icp-partnership/]
[3] [LNGFRM] [https://lngfrm.net/maestro-and-icp-deliver-trustless-bitcoin-defi/]
[4] [Invezz] [https://invezz.com/news/2025/07/22/maestro-teams-up-with-icp-to-bring-ordinals-runes-to-cross-chain-bitcoin-defi/]
[5] [Chainwire] [https://chainwire.org/newsroom/]
[6] [Stocktwits] [https://stocktwits.com/symbol/ICP.X]

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