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Several biotech companies, including Clene, Werewolf Therapeutics, Biomea Fusion, Denali Therapeutics, TScan Therapeutics, Nyxoah SA, and Dyne Therapeutics, posted notable gains in after-hours trading on December 2, 2025. Clene's shares surged 8.53% ahead of an ALS update, while Werewolf and Biomea Fusion climbed 6.12% and 7.31%, respectively. Denali Therapeutics rose 3.14%, and Dyne Therapeutics gained 4.80%.

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