BioMarin Plummets 3.58% Amid 62% Surge in Volume to Rank 495th as Institutional Buyers Pile In and Analysts Split on Prospects

On August 8, 2025, BioMarin Pharmaceuticals (BMRN) closed down 3.58% with a daily trading volume of $200 million, marking a 62.17% increase from the prior day’s activity. The stock ranked 495th in trading volume among listed equities. Recent institutional activity included DNB Asset Management and Aequim Alternative Investments acquiring shares, while Frontier Capital Management reduced its position. Analyst coverage remained mixed, with UBS Group and Cantor Fitzgerald maintaining overweight/buy ratings, while Wedbush and RBC issued neutral or hold recommendations.

Key developments included the European Commission’s positive CHMP opinion to expand VOXZOGO’s indication for achondroplasia in children aged 4 months and older. This regulatory progress followed Phase 3 trial data highlighting long-term growth benefits, presented at the 2023 European Society for Paediatric Endocrinology meeting. Institutional investors, including DnB Asset Management and Tokio Marine Asset Management, increased stakes in the stock during the second half of 2025, reflecting confidence in the pipeline and commercial prospects.

Analyst sentiment varied, with Cantor Fitzgerald raising its FY2026 EPS estimate to $4.84 from $4.29, significantly above the $3.15 consensus. Truist Financial and Guggenheim reiterated buy ratings, while Wedbush maintained an outperform stance. However, RBC and Wedbush also issued neutral or hold recommendations, underscoring cautious expectations. BioMarin’s R&D Day on September 12 highlighted its innovative pipeline, including ROCTAVIAN for hemophilia A, which saw its first European patient treated commercially in August.

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