Axsome Therapeutics Doses First Patient in FORWARD Phase 3 Trial for Fibromyalgia

Thursday, Jan 15, 2026 7:03 am ET1min read
AXSM--

Axsome Therapeutics has initiated the FORWARD Phase 3 trial for AXS-14 (esreboxetine) to treat fibromyalgia. The first patient has been dosed, marking the beginning of the trial. Patients will be randomly assigned to receive either AXS-14 or a placebo after a 12-week open-label treatment period. The primary endpoint of the trial is the time from randomization to loss of therapeutic response.

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