Avadel Faces Board Shake-Up Demand from ASL Amid Sleep Drug Rollout Controversy

Monday, Jun 30, 2025 9:35 am ET1min read

ASL, an activist investor, is pushing for a board shakeup at Avadel Pharmaceuticals over concerns about the company's handling of its sleep drug rollout. ASL is reportedly unhappy with Avadel's decision to partner with Jazz Pharmaceuticals for the commercialization of its sleep drug, ZILDZA, in the US. ASL believes that Avadel's partnership with Jazz will negatively impact the company's ability to maximize the potential value of ZILDZA.

Avadel Pharmaceuticals is facing pressure from activist investor ASL Strategic Value Fund, which has called for the company's entire board of directors to be voted out at the upcoming annual meeting. ASL alleges that Avadel mishandled the launch of its key drug, Lumryz, leading to missed revenue opportunities [1].

According to a letter viewed by The Wall Street Journal, ASL claims that Avadel's partnership with Jazz Pharmaceuticals for the commercialization of its sleep drug, ZILDZA, in the US will negatively impact the company's ability to maximize the potential value of ZILDZA. ASL has a $15 million stake in Avadel and plans to vote against all director nominees at the company's annual meeting scheduled for late July [1].

Avadel has responded by stating that the board proactively engages with shareholders and that its directors have made personal investments in the company. The company continues to focus on "unlocking the full value of Lumryz" despite the ongoing litigation with Jazz Pharmaceuticals over patent disputes [1].

The stock market has been volatile for Avadel, with the company's stock price rising by 16.4% over the past year despite a weak performance across the biopharma sector. The SPDR S&P Biotech ETF is down 9.3% over the past year, while the S&P 500 has gained 5.2% [1].

In a separate development, an appeals court affirmed a favorable FDA ruling for Avadel in its Lumryz litigation with Jazz Pharmaceuticals. The ruling upheld the FDA's approval of Lumryz, validating its clinical superiority over Jazz's twice-nightly oxybate products [2][3]. Avadel's shares rose 3.3% in premarket trading following the ruling [3].

ASL's push for a board shakeup comes amidst a broader trend of activist investors seeking to influence corporate governance and strategy. Investors will be closely watching Avadel's annual meeting to see how the board responds to ASL's demands.

References:
[1] https://stocktwits.com/news-articles/markets/equity/avadel-pharmaceuticals-under-fire-investor-reportedly-demands-board-ouster-sale-talks-1-b-in-damages/chmZReWRRe7
[2] https://www.morningstar.com/news/dow-jones/202506304037/appeals-court-affirms-favorable-fda-ruling-for-avadel-in-lumryn-litigation
[3] https://finance.yahoo.com/news/avadel-pharmaceuticals-announces-unanimous-appeals-110000157.html

Avadel Faces Board Shake-Up Demand from ASL Amid Sleep Drug Rollout Controversy

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