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Arvinas (ARVN) reported Q3 2025 earnings on Nov 5, 2025, with revenue declining sharply but losses narrowing. The company exceeded revenue expectations while reducing its net loss by 28.7% year-over-year, signaling operational improvements.
Revenue
. The decline was attributed to the expiration of a Novartis license agreement, .
Earnings/Net Income
Arvinas narrowed its net loss to $-35.10 million ($0.48 per share) in Q3 2025, . This marked the company’s strongest net loss reduction in eight years, driven by cost-cutting measures and reduced R&D spending.
Post-Earnings Price Action Review
Buying
shares on revenue beats and holding for 30 days shows potential due to Arvinas’ robust clinical pipeline and strategic cost reductions. , . , which signals operational efficiency. Analysts maintain a “buy” rating with a 26.6% upside to the $13.00 price target. However, risks persist, including revenue declines and clinical trial uncertainties.CEO Commentary
CEO John Houston highlighted progress in clinical programs, including Phase 1 data for ARV-102 and preclinical results for ARV-806 and ARV-027. The company emphasized its “data-rich period” with multiple readouts in 2026 and a focus on strategic partnerships, such as the Pfizer collaboration for vepdegestrant commercialization.
Guidance
, 2025, . , 2026, .
Additional News
$100M Share Buyback Program:
announced a stock repurchase plan, .Pfizer Collaboration Expansion: The company and Pfizer plan to jointly select a commercialization partner for vepdegestrant, ensuring launch readiness if approved by the FDA.
Clinical Pipeline Advancements: Positive Phase 1 results for ARV-102 in Parkinson’s disease and preclinical data for ARV-027 in spinal bulbar muscular atrophy were highlighted, reinforcing the company’s focus on neurology and oncology.
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