Amgen’s Shares Plummets 5.14% Despite Record $9.2B Revenue, Ranking 63rd in $1.31B Volume

Generated by AI AgentAinvest Market Brief
Wednesday, Aug 6, 2025 10:01 pm ET1min read
Aime RobotAime Summary

- Amgen shares fell 5.14% on August 6, 2025, with $1.31B volume, despite Q2 adjusted EPS of $6.02 and $9.2B revenue, driven by strong sales of Evenity, Repatha, and Otezla.

- Biosimilars contributed 40% YoY growth, but patent expirations for Prolia/Xgeva in 2025-2026 pose risks as market share erodes.

- The company raised 2025 revenue guidance to $35-36B and adjusted EPS to $20.20-$21.30, citing R&D costs and tariff impacts, while projecting 45% operating margin.

- MariTide’s phase III trials for a monthly-dosed GIPR/GLP-1 diabetes/obesity drug highlight differentiation from Eli Lilly and Novo Nordisk.

- A high-volume stock trading strategy (top 500 by daily volume) generated 166.71% returns since 2022, underscoring liquidity-driven approaches in volatile markets.

Amgen (AMGN) fell 5.14% on August 6, 2025, with a trading volume of $1.31 billion, ranking 63rd in the market. The biopharma giant reported Q2 2025 adjusted earnings of $6.02 per share, exceeding estimates, driven by 9% revenue growth to $9.2 billion. Key products like Evenity, Repatha, and Otezla delivered strong sales, while biosimilars contributed 40% year-over-year growth. However, patent expirations for Prolia and Xgeva in 2025-2026 pose risks as biosimilars erode market share.

Despite robust revenue and profit beats, Amgen’s shares dipped in after-hours trading. The company raised 2025 revenue guidance to $35-36 billion and adjusted EPS to $20.20-$21.30, citing R&D investments and potential tariff impacts. Operating margin is now projected at ~45%, down from prior forecasts, reflecting higher research costs. Meanwhile, the diabetes/obesity pipeline remains a focus, with MariTide’s phase III trials underway. This dual-action GIPR/GLP-1 drug offers monthly dosing, differentiating it from competitors like

and .

The strategy of purchasing the top 500 stocks by daily trading volume and holding them for one day delivered a 166.71% return from 2022 to the present, outperforming the benchmark by 137.53%. This highlights the effectiveness of liquidity-driven approaches in volatile markets, particularly for high-volume equities. The results underscore the importance of short-term trading strategies leveraging market concentration and rapid responsiveness to macroeconomic shifts.

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