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Amgen Inc. (NASDAQ:AMGN) reported mixed trading activity on August 7, 2025, with a 0.01% gain and a trading volume of $0.74 billion, ranking 146th in the market. The stock’s muted movement followed the release of its Q2 2025 earnings, where the biopharmaceutical giant demonstrated robust revenue growth and strategic momentum across key therapeutic areas. Total revenue rose 9% year-over-year to $9.2 billion, driven by double-digit sales increases from 15 products, including Repatha and EVENITY, which grew 31% and 32%, respectively. The rare disease segment expanded 19% to nearly $1.4 billion, while biosimilars sales surged 40% to $661 million. However, Prolia sales declined 4% due to pricing pressures, highlighting the sector’s ongoing challenges with net price erosion.
Amgen’s guidance for 2025 remains optimistic, projecting total revenue between $35 billion and $36 billion and non-GAAP earnings per share of $20.20 to $21.30. The company emphasized its pipeline advancements, including the obesity candidate MariTide and the cardiovascular siRNA therapy olpasiran, as key drivers for long-term growth. Management also highlighted disciplined R&D spending, with a 18% year-over-year increase to $1.7 billion, reflecting confidence in late-stage programs. Despite near-term headwinds from tariffs and pricing dynamics, Amgen’s focus on innovation and market expansion in oncology, inflammation, and rare diseases positions it to capitalize on unmet medical needs.
A strategy of purchasing the top 500 stocks by daily trading volume and holding them for one day yielded a 166.71% return from 2022 to the present, significantly outperforming the benchmark return of 29.18% by 137.53%. This underscores the role of liquidity concentration in short-term stock performance, particularly in volatile markets, where high-volume equities can amplify returns through rapid price movements and market participation. The results highlight the potential for liquidity-focused strategies to exploit market dynamics, though investors must weigh the inherent risks of short-term volatility and sector-specific exposure.

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