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Amarin Corporation presented in vitro data at the European Society of Cardiology Congress 2025 that highlights the mechanism of action for its drug VASCEPA/VAZKEPA. The data shows that eicosapentaenoic acid (EPA) modulates inflammasome activation in monocyte-derived macrophages and inhibits lipoprotein(a) oxidation, which may contribute to reducing inflammation and cardiovascular risk. The findings provide additional insight into the mechanisms of action for VASCEPA/VAZKEPA and its potential impact on reducing cardiovascular events in at-risk patients.

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