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On October 9, 2025, , ranking 237th in market activity. , reflecting modest investor interest amid broader market dynamics.
Recent developments highlight Alnylam’s focus on advancing its pipeline of RNAi therapeutics. A key catalyst this quarter has been regulatory progress for its lead candidate, . Analysts noted that the company’s ability to maintain a consistent development timeline, despite industry-wide supply chain challenges, has bolstered its reputation for operational reliability.
Market participants also observed increased institutional buying activity in late September, driven by renewed interest in biotech sector fundamentals. While the stock’s valuation remains anchored to its R&D milestones, . However, long-term investors remain cautious about the competitive landscape in rare disease treatments.
To set up and run this back-test robustly, I need a few additional details about how you’d like the strategy implemented: 1. Market universe—Which exchange(s) should the stocks come from (e.g., all U.S. listed equities, only S&P 500 constituents, China A-shares, etc.)? 2. Re-balancing mechanics—Do we buy the top-500 stocks ranked by the same day’s volume at that day’s close and sell them all at the next day’s close (1-day holding period, equal-weight each day)? 3. Data conventions—Use split-/dividend-adjusted close prices, or raw closes? Once you confirm these points, .

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