Akero Therapeutics Reports Efruxifermin's Antifibrotic Effects in Phase 2b Trials.

Friday, Nov 7, 2025 7:10 am ET1min read

Akero Therapeutics announced new findings from the SYMMETRY and HARMONY Phase 2b trials of efruxifermin in patients with compensated cirrhosis due to metabolic dysfunction-associated steatohepatitis (MASH). Post-hoc analyses corroborated antifibrotic effects and indicated potential to reduce disease progression in F4c patients. Digital pathology reinforced fibrosis improvements in the HARMONY trial.

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