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Adlai Nortye Ltd. will present AN4035 data at the AACR-NCI-EORTC International Conference. The company's clinical-stage biotechnology focuses on cancer therapies. Highlights include AN4035's strong intracellular payload retention and potent bystander-killing effect, inducing deep regression in CEACAM5-positive/RAS-addicted CDX and PDX models with a 73% objective response rate. Preliminary toxicology profile in cynomolgus monkeys is favorable.
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