ADC Therapeutics Updates LOTIS-7 Trial Results for ZYNLONTA and Glofitamab in Relapsed or Refractory DLBCL

Wednesday, Dec 3, 2025 10:56 am ET1min read

ADC Therapeutics SA (ADCT) has announced updated results from the LOTIS-7 trial evaluating ZYNLONTA plus Glofitamab in relapsed or refractory DLBCL. The trial achieved its primary endpoint of overall response rate, with a 95% ORR observed in the combination arm. The company plans to submit data to regulatory authorities for potential approval.

ADC Therapeutics Updates LOTIS-7 Trial Results for ZYNLONTA and Glofitamab in Relapsed or Refractory DLBCL

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