Aclaris Therapeutics Presents Positive Results for ATI-2138 in Atopic Dermatitis Trial
ByAinvest
Friday, Mar 27, 2026 10:12 am ET1min read
ACRS--
Aclaris Therapeutics presented positive results from its Phase 2a trial of ATI-2138, an oral covalent inhibitor of ITK and JAK3, at the 2026 American Academy of Dermatology Annual Meeting. Patients receiving ATI-2138 experienced improvements in disease severity, itch, affected body surface area, and quality of life measures. The treatment was well-tolerated, with near complete and sustained ITK target occupancy observed across the dosing interval. Aclaris is focused on developing novel product candidates for immuno-inflammatory diseases.

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