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Aclaris Therapeutics (ACRS) reported fiscal 2025 Q3 earnings on Nov 6, 2025, with revenue and net loss figures diverging from expectations. The company exceeded revenue estimates despite a 24.1% year-over-year decline, . CEO Dr. Neal Walker emphasized progress in its pipeline, including Phase 2a trial success for ATI-2138 and a cash runway extending through mid-2028.
Revenue
Total revenue for
declined to $3.30 million in 2025 Q3, . The decrease was attributed to reduced milestones under prior licensing agreements, .Earnings/Net Income
, . Earnings per share (EPS) fell to -$0.12, . The EPS result beat the $-0.13 consensus estimate, reflecting a narrower-than-expected loss despite sustained operational challenges.
Post-Earnings Price Action Review
Aclaris Therapeutics’ stock price declined 0.87% on the latest trading day and 8.84% over the past week, contrasting with a 23.37% monthly gain. The mixed performance highlights investor uncertainty amid the company’s prolonged losses and reliance on non-dilutive financing. Analysts remain cautiously optimistic, with seven “buy” ratings and no “sell” calls, .
CEO Commentary
Dr. Neal Walker highlighted advancements in Aclaris’ pipeline, , which demonstrated favorable tolerability and clinical improvements. He reiterated confidence in the company’s cash runway through 2028 and outlined plans to advance four clinical-stage candidates in 2026, including and biologics.
Guidance
Aclaris expects to initiate Phase 2 trials of ATI-2138 in additional indications (e.g., lichen planus) in H1 2026, . , .
Additional News
Recent non-earnings developments include:
Pipeline Advancements.
Zacks Rank Update: The stock was assigned a Zacks Rank #3 (Hold), .
Capital Strategy: Management emphasized opportunities for non-dilutive financing, including , .

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