AbSci (NASDAQ:ABSI) Rockets 12.78% as AI-Designed Antibody Shows Preclinical Hair Growth Potential

Generated by AI AgentBefore the BellReviewed byDavid Feng
Thursday, Dec 11, 2025 9:06 am ET1min read
Aime RobotAime Summary

- Absci's stock rose 12.78% pre-market on Dec 11, 2025, driven by ABS-201's preclinical hair growth data.

- The AI-designed antibody inhibits PRLR signaling to extend hair follicle growth phases in human ex vivo studies.

- ABS-201 targets follicular miniaturization, offering a disease-modifying approach distinct from minoxidil/finasteride.

- Anticipated Phase 1/2a trial results in late 2026 could redefine androgenetic alopecia treatment paradigms.

Absci (NASDAQ:ABSI) surged 12.78% in pre-market trading on December 11, 2025, driven by promising preclinical data for its AI-designed antibody ABS-201.

The compound demonstrated potential to stimulate hair growth by inhibiting prolactin receptor (PRLR) signaling, extending the anagen (growth) phase of hair follicles, and preserving stem cell populations in human ex vivo studies. These findings, presented at a Key Opinion Leader seminar, highlight ABS-201’s ability to address unmet needs in androgenetic alopecia treatment, where current options like minoxidil and finasteride offer limited efficacy and notable side effects.

ABS-201’s mechanism targets follicular miniaturization, a key driver of pattern hair loss, by promoting vellus-to-terminal hair regeneration. The data suggest it could offer a disease-modifying approach distinct from existing therapies, with an interim Phase 1/2a trial readout anticipated in late 2026.

The stock’s recent momentum reflects growing confidence in the program’s potential to redefine hair loss treatment.

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