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89bio, Inc. has been removed from the S&P Global BMI Index. The company is a clinical-stage biopharmaceutical firm focused on developing treatments for liver and cardio-metabolic diseases. Its lead product candidate, pegozafermin, is being developed for NASH and SHTG. Pegozafermin is a glycoPEGylated analog of FGF21 designed to protect against proteolysis and reduce renal clearance. The company conducted a Phase I clinical trial to evaluate its safety, tolerability, and pharmacokinetics.

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