Tempus AI Shares Soar on Strategic AI Healthcare Deals as $740M Volume Ranks 143rd in Market Activity

Tempus AI (TEM) closed on September 8, 2025, , , . The stock’s performance was driven by strategic partnerships and acquisitions strengthening its AI healthcare leadership. The company announced a collaboration with Northwestern Medicine to integrate its generative AI co-pilot, David, into the health system’s EHR platform, marking a significant expansion of its clinical AI applications. Additionally, , enhancing its data and technology capabilities in precision medicine.

Analyst sentiment remained cautiously optimistic. TD Cowen raised Tempus’s price target following growth in genomic volumes, while Morgan Stanley highlighted its participation in the Global Healthcare Conference as a platform to showcase its AI-driven innovations. Despite mixed market conditions, , reflecting improved operational efficiency and expanding margins. However, risk management strategies were emphasized as volatility persisted amid broader market fluctuations.

Backtesting parameters for Tempus’s stock strategy require defining market universe, signal execution timing, weighting methods, frictional costs, and risk controls. Key decisions include selecting U.S.-listed stocks, determining ranking dates and execution prices, allocating capital via equal or volume-weighted methods, and accounting for transaction costs. , 2022, to the present, .