Penny Stocks on the Move: Today’s Top Gainers and Biggest Decliners

Opening Paragraph:
On September 25, 2025, Cycurion, Inc. (CYCU) surged 68.75% to rank as the top-performing penny stock, while Ambipar Emergency Response (AMBI) plummeted 51.03% to emerge as the day’s steepest decliner.

Top Gainers
Cycurion, Inc. (CYCU)
Cycurion, Inc. (CYCU), a software company, surged 68.75% to close at $0.486 (intraday high: $0.539), ranking first among penny stocks today. The move follows its recent $1 million equity exchange with IQSTEL, triggering a shareholder dividend distribution. Increased institutional holdings in IQSTEL were noted on Sep. 24. Analysts observe the surge aligns with a projected $93 billion AI cybersecurity market by 2030, boosting sentiment for firms like Cycurion in the sector.

New Era Energy & Digital, Inc. (NUAI)
NUAI stock surged 49.84%, ranking as the day's second-biggest gainer among penny stocks, closing at $1.38 after hitting an intraday high of $1.44 within the Oil, Gas & Consumable Fuels sector. Key developments driving the move include reports detailing the September 24 completion of Phase One engineering for the company's flagship AI data center campus and the company signing a letter of intent earlier this month for its Texas subsidiary to deliver a proprietary power supply to that campus, alongside a September 17 memorandum of understanding for a major fiber network across Texas; analysts note these strategic infrastructure advancements potentially signaled significant project momentum to the market.

Pop Culture Group Co., Ltd (CPOP)
Entertainment sector stock CPOP surged 45.91%, ranking 3rd among penny stocks today, hitting an intraday high of $2.60 before closing at $2.05. The company's price jump followed its September 25th announcement of a plan to accumulate 1,000 Bitcoin over the next year to fund a $100 million crypto entertainment initiative integrating AI and blockchain for live events. Further reports on September 24th highlighted Pop Culture Group's ambitious move into the trillion-dollar crypto entertainment market.

Plus Therapeutics, Inc. (PSTV)
Plus Therapeutics, Inc., a biotechnology firm, surged 39.36% today, ranking as the fourth-largest gainer among penny stocks. The stock reached an intraday high of $0.621 and closed at $0.563. Investor sentiment was boosted by news of a national coverage agreement with UnitedHealthcare for its cancer diagnostics, disclosed today, alongside the September 22 announcement of a $1.9 million funding advance for targeted radiotherapeutics development.

Sunrise New Energy Co., Ltd. (EPOW)
Sunrise New Energy Co., Ltd. (EPOW), operating in the Electronic Equipment, Instruments & Components sector, saw its stock surge 38.27% today, ranking as the fifth-largest gainer in the penny stock market. Shares reached an intraday high of $1.14 before closing at $1.12.
Reports indicate a return to profitability in July and August 2025, achieving a combined net profit exceeding $0.57 million. Additionally, analysts highlight the commencement of construction on September 19 for a significant $64 million graphite anode production facility expansion as key catalysts.

Top Decliners
Ambipar Emergency Response (AMBI)
Ambipar Emergency Response (AMBI) collapsed 51.03% today, ranking as the penny stock market’s worst performer. Shares hit an intraday low of $1.64 before closing at $1.69 in the Commercial Services and Supplies sector. The selloff coincides with its parent company filing for court-supervised insolvency and receiving emergency creditor protection on September 24, alongside announced leadership changes including the CFO role.

Seastar Medical Holding Corp (ICU)
Seastar Medical Holding Corp (ICU), operating in Healthcare Equipment and Supplies, experienced a sharp decline today, plummeting 50.97% to close at $0.608 after hitting an intraday low of $0.54, ranking it as the second-worst performer among penny stocks. Despite reporting positive trial progress two days prior, including a DSMB recommendation to continue its NEUTRALIZE-AKI study and an enrollment target increase to 339 patients, significant investor concern stemmed from concurrent disclosures of abrupt changes to the company's executive leadership. Reports indicate the Chief Financial Officer, David Green, was terminated without cause on the same date as the trial updates were announced, overshadowing the scientific developments and fueling the significant market sell-off.

Li Bang International Corporation Inc. (LBGJ)
Li Bang International Corporation Inc. (LBGJ), operating in the Household Durables sector, plummeted 50.93% today—ranking as the third-worst performer among penny stocks. Shares hit an intraday low of $0.52 before closing at $0.66. Recent undisclosed corporate developments have triggered market unease, with concerns mounting on September 22, 2025 over strategic initiatives and September 24, 2025 regarding governance alignment pressures.

Zhengye Biotechnology Holding Limited (ZYBT)
Zhengye Biotechnology (ZYBT), operating in the Pharmaceuticals sector focusing on veterinary vaccines, experienced significant selling pressure today, plummeting 39.64%, marking the day's 4th largest decline among penny stocks. The stock touched an intraday low of $2.8 before closing at $3. This sharp drop follows reports indicating the company's fiscal year 2024 earnings release on July 3, 2025, alongside sustained investor scrutiny surrounding its market position post-IPO earlier this year.

Cemtrex, Inc. (CETX)
Cemtrex, Inc. (CETX) plummeted 33.92% today, marking the fifth-steepest decline among penny stocks. Shares touched an intraday low of $0.40 before settling at $0.415. The company operates in the Electronic Equipment, Instruments and Components sector. Today’s selloff directly followed the approval of a 1-for-15 reverse stock split effective September 29th to meet Nasdaq’s $1 minimum bid requirement, amplifying investor concerns over dilution and compliance viability reports indicate.