OSR Holdings shares jump 21.59% intraday as Vaximm AG signs $20M licensing deal with BCM Europe and appoints new CEO to expand immunotherapy business.

think> Okay, let's tackle this query. The user wants me to transform a given text into a concise news headline following specific rules. First, I need to understand the input thoroughly. The company here is OSR Holdings, and the percentage change is 21.59458211%. I should round that to two decimal places, so that's 21.60%. The time period is intraday, so I need to mention "intraday trading". Next, the reasons for the price movement are listed in three points. Let me parse each one. The first point is about Vaximm AG signing a non-binding term sheet with BCM Europe for a $20M upfront and up to $815M in milestones. The second is the appointment of Andreas Niethammer as CEO to expand their immuno-oncology business. The third is insider buying by 10 insiders and an upgrade from Strong Sell to Buy. I need to combine these reasons concisely. The key points are the term sheet, the CEO appointment, insider buying, and the analyst upgrade. I should mention each briefly without getting too detailed. The example given in the prompt shows including the subsidiary and the project details, so here I should mention Vaximm AG's agreement and the CEO appointment as the main drivers, then the insider activity and upgrade as supporting factors. I also need to ensure the company name is unchanged, so "OSR Holdings" stays as is. The percentage is 21.60%, and the time period is intraday. The structure should follow the example: company name, percentage, time period, then the reasons in a sentence or two. Wait, the example uses a period and a line break between the main reason and the company description. But in the user's example, after the initial line, there's a paragraph about the company's focus. However, the user's instruction says to provide a brief reason for the price movement, so maybe I need to include all the reasons in the same sentence or two, not separate paragraphs. Let me check the rules again. The transformation rules state to provide a brief reason for the price movement, retaining key information. So I need to include all three reasons but in a concise manner. Let me structure it as: OSR Holdings surged 21.60% intraday, driven by Vaximm AG's non-binding term sheet with BCM Europe for a $20M upfront and up to $815M in milestones, the appointment of Andreas Niethammer as CEO to expand immuno-oncology efforts, insider buying by 10 insiders, and an analyst upgrade from Strong Sell to Buy. That seems to cover all points concisely. I should also note that the user might have a typo in the percentage (21.59458211% rounds to 21.59% or 21.60%?). Wait, 0.59458211 is more than 0.595, so when rounding to two decimal places, it would be 21.59%? Wait, no, 21.59458211 is 21.59% when rounded to two decimal places because the third decimal is 4, which is less than 5. Wait, no, the third decimal is 4 (21.594...), so rounding to two decimals would be 21.59%. But the user's example had 4.230769% rounded to 4.23%. Wait, 4.230769% is approximately 4.23% when rounded to two decimal places. Similarly, 21.59458211% is 21.59% when rounded to two decimals. But wait, the third decimal is 4, so it's 21.59%. But maybe the user expects 21.59% or 21.60%? Let me check the exact value. The number is 21.59458211%. The third decimal digit is 4, so when rounding to two decimals, it's 21.59%. So the correct rounding is 21.59%. But the user's example had 4.230769% rounded to 4.23%, which is correct. So in this case, 21.59458211% should be 21.59%. But the user might have made a mistake here. Wait, the input says "21.59458211%", and the example had "4.230769%" rounded to 4.23%. So the correct rounding here is 21.59.