Mizuho Financial Group Advances Space Molecular Crystallization with Gold Nanostructure Technology

Mizuho Financial Group Inc (MFG) has announced a breakthrough in space molecular crystallization using gold nanostructure technology. The experiment successfully demonstrated the potential for high-quality and larger protein crystals in a microgravity environment, but the overall number of crystals generated was lower than prior Earth-based experiments. This achievement positions MFG and TANAKA MIRAI Lab as pioneers in the intersection of precious metals and space technology, potentially opening new markets in biotechnology and pharmaceuticals.

Mizuho Financial Group Inc. (MFG) and TANAKA MIRAI Lab. have jointly announced a significant breakthrough in space molecular crystallization using gold nanostructure technology. The experiment, conducted in a microgravity environment aboard the International Space Station (ISS), successfully demonstrated the potential for generating high-quality and larger protein crystals. This achievement positions MFG and TANAKA MIRAI Lab. as pioneers in the intersection of precious metals and space technology, potentially opening new markets in biotechnology and pharmaceuticals.

The experiment utilized an experimental unit developed by TANAKA MIRAI Lab., which employs Au (gold) nanostructure formation technology. The unit was installed in the SpaceX CRS-32 spacecraft and launched to the ISS in April 2025. After a month of observation and experimentation, the unit returned to Earth with successful protein crystallization results [1].

The experiment involved the use of the counter-diffusion method, where protein solutions were placed in capillaries with nano-level Au particles aligned on the inner walls. This method, combined with the microgravity environment of space, facilitated the generation of protein crystals. The results indicated that the use of Au nanostructures significantly improved the crystal generation rate compared to capillaries without Au nanostructures [1].

While the overall number of crystals generated in space was lower than prior Earth-based experiments, the quality and size of the crystals were higher. This is attributed to the absence of gravity, which eliminates convection and sedimentation effects that can degrade crystal quality on Earth [1].

The success of this experiment highlights the potential for space-based research in advancing drug discovery and understanding biological functions. TANAKA MIRAI Lab. and MFG are now positioned to leverage this technology to drive innovation in biotechnology and pharmaceuticals, potentially creating new market opportunities [1].

References:
[1] https://www.finanznachrichten.de/nachrichten-2025-08/66241527-mizuho-financial-group-tanaka-precious-metal-group-and-tanaka-mirai-lab-successfully-carries-out-space-protein-crystallization-experiments-011.htm