Graham Holdings's 15-min chart signals bearish trends with MACD Death Cross, RSI Overbought.

According to the 15-minute chart of Graham Holdings, a MACD Death Cross, RSI Overbought, and KDJ Death Cross were triggered on October 21, 2025, at 12:45. This indicates that the stock price has the potential to continue falling, as it has risen too rapidly and exceeds the fundamentals' support. Furthermore, the momentum of the stock price is shifting towards the downside, with a potential to further decrease.

Talphera Inc. (TLPH), a specialty pharmaceutical innovator focusing on therapies for critical care environments, has recently reported its Q2 2025 financial results and provided updates on its clinical trials. The company's stock has been the subject of significant attention, with recent technical indicators suggesting potential downward momentum.

Financial Results

The company reported a net loss of $3.5 million ($0.10 per share) in Q2 2025, a slight improvement over the $3.8 million loss in Q2 2024. Operating expenses decreased to $3.7 million from $4.3 million year-over-year. Notably, the company secured a three-tranche financing of up to $14.8 million, with the first tranche of $4.9 million closed in April 2025. The cash position stood at $6.8 million as of June 30, 2025. Talphera revised its 2025 cash operating expense guidance to $16-17 million, down from the previous $17-19 million range .

Clinical Trial Milestones

Talphera has made significant progress in its NEPHRO CRRT pivotal trial, enrolling 17 patients, representing approximately 25% of the targeted 70-patient enrollment. This achievement fulfills a requirement for the second tranche of their March 2025 three-tranche financing agreement. The company reports an accelerated recruitment rate from new profile clinical sites, with over 90% of enrolled patients coming from these new locations. With six additional sites expected to begin enrollment in Q3, Talphera remains confident in completing the study by the end of 2025 .

Market Indicators

According to the 15-minute chart of Graham Holdings, a MACD Death Cross, RSI Overbought, and KDJ Death Cross were triggered on October 21, 2025, at 12:45. This indicates that the stock price has the potential to continue falling, as it has risen too rapidly and exceeds the fundamentals' support. Furthermore, the momentum of the stock price is shifting towards the downside, with a potential to further decrease .

Conclusion

Talphera Inc. has shown resilience in its financial performance and clinical trial progress, despite challenging market conditions. Investors should closely monitor the company's earnings and clinical trial milestones, as well as the broader market indicators that may impact its stock price. As always, thorough research and a balanced investment strategy are recommended.