Glenmark Pharma Surges on Licensing Deal with AbbVie for Cancer Treatment
PorAinvest
viernes, 11 de julio de 2025, 9:50 am ET1 min de lectura
ABBV--
Under the terms of the agreement, Glenmark's subsidiary Ichnos Glenmark Innovation (IGI) will collaborate with AbbVie to develop, manufacture, and commercialize ISB 2001, a first-in-class trispecific T-cell engager designed to treat multiple myeloma. AbbVie will handle development and commercialization in North America, Europe, Japan, and Greater China, while Glenmark will focus on manufacturing and marketing the therapy in Emerging Markets.
ISB 2001, currently in Phase 1 clinical development, targets BCMA and CD38 on myeloma cells and CD3 on T cells. The therapy has shown promising results, with a 79% overall response rate and 30% complete/stringent complete response in a heavily pretreated patient population. It has also received Orphan Drug Designation and Fast Track Designation from the U.S. FDA for relapsed/refractory multiple myeloma.
The licensing deal is expected to significantly boost Glenmark's revenue and further establish the company as a major player in the pharmaceutical industry. AbbVie's extensive presence in the US market and Glenmark's commercial strength in Emerging Markets create complementary access pathways for ISB 2001.
This deal highlights the increasing interest in partnerships between pharmaceutical companies to accelerate the development and commercialization of innovative therapies. The collaboration between Glenmark and AbbVie reflects a shared commitment to expanding patient access to transformative multispecifics for patients worldwide.
Glenmark's stock price hit an upper limit of 10% to a record high of Rs 2095.65 following the announcement, indicating strong investor confidence in the company's strategic move. The company's net profit for Q4 March 2025 was Rs 4.65 crore, up from a net loss of Rs 1,218.28 crore in Q4 March 2024, demonstrating its financial resilience and growth potential.
References:
[1] https://www.business-standard.com/markets/capital-market-news/glenmark-pharma-soars-on-abbvie-licensing-deal-for-cancer-therapy-isb-2001-125071100445_1.html
[2] https://www.statnews.com/sponsor/2025/07/07/from-ideas-to-impact-collaborating-on-the-next-generation-of-cancer-breakthroughs/
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Glenmark Pharma has surged after its unit licensed a cancer treatment to AbbVie Inc. The deal highlights the growing demand for cancer treatments and the increasing interest in partnerships between pharmaceutical companies. AbbVie specializes in therapeutic drug research and development, with a significant presence in the US market. The licensing deal is expected to boost Glenmark Pharma's revenue and further establish the company as a major player in the pharmaceutical industry.
Glenmark Pharmaceuticals (Glenmark Pharma) has seen a significant surge in its stock price following the announcement of a major licensing deal with U.S. biopharma giant AbbVie Inc. The deal, which involves the commercialization of Glenmark's lead investigational oncology asset, ISB 2001, has boosted investor confidence and underscored the growing demand for innovative cancer treatments.Under the terms of the agreement, Glenmark's subsidiary Ichnos Glenmark Innovation (IGI) will collaborate with AbbVie to develop, manufacture, and commercialize ISB 2001, a first-in-class trispecific T-cell engager designed to treat multiple myeloma. AbbVie will handle development and commercialization in North America, Europe, Japan, and Greater China, while Glenmark will focus on manufacturing and marketing the therapy in Emerging Markets.
ISB 2001, currently in Phase 1 clinical development, targets BCMA and CD38 on myeloma cells and CD3 on T cells. The therapy has shown promising results, with a 79% overall response rate and 30% complete/stringent complete response in a heavily pretreated patient population. It has also received Orphan Drug Designation and Fast Track Designation from the U.S. FDA for relapsed/refractory multiple myeloma.
The licensing deal is expected to significantly boost Glenmark's revenue and further establish the company as a major player in the pharmaceutical industry. AbbVie's extensive presence in the US market and Glenmark's commercial strength in Emerging Markets create complementary access pathways for ISB 2001.
This deal highlights the increasing interest in partnerships between pharmaceutical companies to accelerate the development and commercialization of innovative therapies. The collaboration between Glenmark and AbbVie reflects a shared commitment to expanding patient access to transformative multispecifics for patients worldwide.
Glenmark's stock price hit an upper limit of 10% to a record high of Rs 2095.65 following the announcement, indicating strong investor confidence in the company's strategic move. The company's net profit for Q4 March 2025 was Rs 4.65 crore, up from a net loss of Rs 1,218.28 crore in Q4 March 2024, demonstrating its financial resilience and growth potential.
References:
[1] https://www.business-standard.com/markets/capital-market-news/glenmark-pharma-soars-on-abbvie-licensing-deal-for-cancer-therapy-isb-2001-125071100445_1.html
[2] https://www.statnews.com/sponsor/2025/07/07/from-ideas-to-impact-collaborating-on-the-next-generation-of-cancer-breakthroughs/

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