Dyne Therapeutics Common Stock Under Lock-Up Agreement Until August 30, 2025

Dyne Therapeutics' common stock is subject to a lock-up agreement ending on August 30, 2025. The agreement prohibits directors and officers from selling or transferring shares without prior written consent from Morgan Stanley and Jefferies. The lock-up period begins on June 30, 2025, and lasts for 60 days.

Dyne Therapeutics Inc. (NASDAQ: DYN) stock experienced a significant 4.1% increase following a positive upgrade from Raymond James analyst Martin Auster. The upgrade, from "Outperform" to "Strong Buy," was accompanied by an increased price target of $35.00, up from $31.00 [1].

The upgrade reflects Auster's increased confidence in Dyne Therapeutics' upcoming DYNE-251 registrational cohort readout, expected in late 2025, and a potential Biologics License Application (BLA) filing in early 2026. Auster's optimism is based on the differentiated profile of DYNE-251 compared to Exondys 51, confidence in a path to accelerated approval, and an underappreciated market opportunity in exon 51 Duchenne muscular dystrophy (DMD) [1].

The DYNE-251 registrational cohort results could serve as a key catalyst for Dyne Therapeutics, potentially de-risking a $500-700 million-plus peak annual opportunity in the U.S. and over $1 billion worldwide. These results could also establish the company's DMD pipeline as a dominant narrative and elevate floor value ahead of 2026 DM1 catalysts, including the DYNE-101 registrational cohort readout expected around mid-2026 and a BLA filing anticipated in late 2026 [1].

It is also worth noting that Dyne Therapeutics' common stock is subject to a lock-up agreement ending on August 30, 2025. The agreement, which prohibits directors and officers from selling or transferring shares without prior written consent from Morgan Stanley and Jefferies, began on June 30, 2025, and lasts for 60 days [2].

References:

[1] https://www.investing.com/news/stock-market-news/dyne-therapeutics-stock-rises-after-raymond-james-upgrade-to-strong-buy-93CH-4209525

[2] (Provided writing topic)