Bitcoin's $250K Hurdle Hinges on Fed Policy and Liquidity Shifts

Bitcoin’s potential for growth in 2025 faces a complex mix of challenges and opportunities as rising global liquidity and the Fed’s policy decisions play a pivotal role in shaping market sentiment. Despite optimism around liquidity expansion and institutional adoption, several factors—including derivatives trading volatility, a pause in institutional investment, and uncertainty around the Federal Reserve’s rate policy—suggest momentum could be constrained in the near term.

Derivatives markets show a heightened risk of mass liquidations in September 2025, with open interest in Bitcoin futures surpassing $220 billion—a monthly high. This reflects increased leverage among traders, who are positioning ahead of major economic events such as the FOMC meeting. CoinGlass data indicates that both long and short positions with high leverage are at risk of being liquidated if Bitcoin moves significantly in either direction. If the price drops to $104,500, long positions could face over $10 billion in losses, while a rise above $124,500 could trigger more than $5.5 billion in short liquidations. Analysts urge traders to manage exposure carefully, particularly as volatility remains a key concern.

Meanwhile, the Federal Reserve’s recent 50-basis-point rate cut has sparked debate over its impact on global liquidity. This marks the first rate reduction since March 2020 and brings the federal funds rate to a range of 4.75%-5.00%. The cut is part of a broader easing stance from the Fed, but projections from the Summary of Economic Projections (SEP) suggest that the pace of rate cuts will slow in 2025, with the long-run rate now at 2.875%. The Fed has maintained its quantitative tightening (QT) program, with the balance sheet reducing by nearly $1.7 trillion from its peak. However, the Reverse Repurchase Agreement (RRP) remains the primary mechanism for managing liquidity, with limited capacity to absorb future reductions.

The interplay between global liquidity and Bitcoin’s price is a central theme among macro analysts. Arthur Hayes, co-founder of BitMEX, has argued that Bitcoin’s trajectory is closely tied to the flow of liquidity into the system, particularly through central-bank actions such as quantitative easing (QE). He notes that as long as the Fed continues to inject liquidity—either through traditional QE or fiscal-driven measures—Bitcoin could see substantial gains. Hayes projects that a shift from QT to QE could drive Bitcoin to $250,000 by year-end 2025, a more than 100% increase from its current price of $116,000.

Yet, despite these bullish forecasts, Bitcoin ETF flows in 2024 revealed mixed trends. The launch of the first spot Bitcoin ETFs in January 2024 drove substantial inflows, with BlackRock’s iShares Bitcoin Trust (IBIT) attracting $13.9 billion in Q1. Fidelity’s Wise Origin Bitcoin Trust (FBTC) also saw strong demand, but Grayscale’s Bitcoin Trust (GBTC) faced significant outflows due to competition from lower-fee alternatives. By mid-2024, inflows had slowed, with institutional investors reassessing strategies in response to Bitcoin’s volatility and broader macroeconomic concerns.

The broader financial market environment remains uncertain, with recent economic indicators signaling potential stagflation and a slowdown in growth. The University of Michigan’s consumer sentiment index dropped to 64.7 in February 2025, the lowest since November 2023, and PMI readings for manufacturing and services have fallen below the 50 expansion threshold. These developments have contributed to a risk-off mood, with both stocks and Bitcoin underperforming. The so-called “Trump trade” that initially drove Bitcoin to record highs appears to have faded, as market participants shift focus to the potential for Fed rate cuts and global liquidity expansion.

Analysts like Jamie Coutts have highlighted that Bitcoin often follows M2 money supply trends with a lag of about 60 days. With global liquidity strengthening in early 2025, Bitcoin could see a rebound by midyear, assuming the trend continues. However, the market’s reaction to liquidity injections is not guaranteed, and factors such as trade tensions and political uncertainty could delay or disrupt this trajectory. The challenge for investors is navigating a landscape where liquidity and institutional behavior are key drivers, but volatility and macroeconomic risks remain significant.

title1 https://www.kdj.com/zh/cryptocurrencies-news/articles/bitcoin-price-prediction-k-move-horizon.html

title2 https://beincrypto.com/september-could-face-new-liquidation-record/

title3 https://www.thecoinrepublic.com/2025/09/18/what-bitcoin-btc-usd-path-to-250000-hinges-on-arthur-hayes-explains/

title4 https://www.coinglass.com/bitcoin-etf

title5 https://blog.amberdata.io/bitcoin-btc-etf-flows-in-2024

title6 https://cointelegraph.com/news/bitcoin-trump-trade-is-over-will-fed-rate-cuts-and-m2-expansion-help

title7 https://am.jpmorgan.com/us/en/asset-management/liq/insights/liquidity-insights/updates/fomc-rate-cut-and-impact-on-global-liquidity-investors/