Bioxcel Therapeutics 2025 Q2 Earnings Widened Net Loss Amid Revenue Drop

Bioxcel Therapeutics (BTAI) reported its fiscal 2025 Q2 earnings on August 12, 2025, highlighting significant revenue decline and a widened net loss despite a reduced per-share loss.

Revenue
Total revenue for Bioxcel Therapeutics plummeted by 89.1% to $120,000 in 2025 Q2, down from $1.10 million in the same period the previous year. Product revenue, net, stood at $120,000, representing the sole revenue segment reported during the quarter.

Earnings/Net Income
The company narrowed its per-share loss to $2.45 from $3.30 in 2024 Q2, reflecting a 25.8% improvement. However, the net loss expanded significantly to $19.19 million, marking a 131.2% increase compared to the $8.30 million loss in the prior-year quarter. This represents the third consecutive year of losses for the firm, underscoring ongoing financial challenges.

Price Action
Shares of Bioxcel Therapeutics surged 21.00% during the latest trading day, with a week-long gain of 128.96% and a monthly surge of 245.18%.

Post-Earnings Price Action Review
A post-earnings trading strategy involving a purchase of BTAI shares on the report date and holding for 30 days yielded a severe loss of -98.49%, underperforming the benchmark by 144.81%. The strategy, marked by a maximum drawdown of 0% and a Sharpe ratio of -0.65, highlights the high volatility and risk associated with the stock.

CEO Commentary
Vimal Mehta, Ph.D., CEO of BioXcel Therapeutics, expressed optimism about the upcoming topline data readout for the SERENITY At-Home Phase 3 trial. The preliminary findings indicate a significantly larger target market for BXCL501 in the at-home setting than originally estimated, potentially exceeding 23 million annual agitation episodes. Mehta emphasized the expanded market opportunity as a key milestone for addressing unmet needs in bipolar disorder and schizophrenia patients.

Guidance
The company expects to report topline results from the SERENITY At-Home Phase 3 trial in August 2025 and plans an FDA meeting to support a potential sNDA submission for label expansion of IGALMI® in the at-home setting. Additionally, non-clinical data on BXCL501 in *Frontiers in Pharmacology* is expected to highlight its potential in chronic stress-related conditions. BioXcel is also evaluating CROs to initiate the TRANQUILITY In-Care Phase 3 trial for Alzheimer’s dementia agitation.

Additional News
Recent news highlights include a surge in global AI investment, strategic corporate realignments in the biotech sector, and a regulatory review of clinical trial expansion protocols. Additionally, a major pharmaceutical firm announced a partnership for Alzheimer’s research, signaling increased interest in neurodegenerative disease therapies.