AC Immune shares rise 14.33% intraday after Phase II VacSYn trial shows ACI-7104.056 may slow Parkinson's progression with 100% immunogenicity and no serious adverse events.

think> Okay, let me start by understanding the user's request. They want me to transform a given Chinese text into a concise news headline following specific rules. The example provided is helpful, so I should refer to that. First, I need to identify the company name. The input mentions "AC Immune盘中 intraday大涨14.33333333%". The company name is AC Immune, so that's straightforward. Next, the percentage change is 14.33333333%, which needs to be rounded to two decimal places. That would be 14.33%. The time period is intraday, so I have to include that in the headline. Now, the reason for the price movement is the key part. The input lists three points. The main one is the positive mid-term results from the Phase II VacSYn trial, showing that the active immunotherapy ACI-7104.056 might slow Parkinson's progression. The trial had 100% immunogenicity response rate and good safety profile with no serious adverse events. Common side effects were 56% injection site reactions. The company is a clinical-stage biopharma focused on precision treatments for neurodegenerative diseases, specifically promoting anti-alpha-synuclein active immunotherapy. I need to condense this into a brief reason. The headline should include the company name, percentage, time period, and the reason. The example uses a structure where the surge is mentioned first, followed by the reason. So, the main points to include are the positive trial results, the therapy's potential to slow Parkinson's, and the safety data. Also, mention that the company is a clinical-stage biopharma focusing on neurodegenerative diseases with active immunotherapy. I should check the rules again: keep the company name unchanged, round the percentage, add the time period, provide a brief reason with key info. Avoid trailing zeros. Make sure the headline is in English. Let me structure it step by step. Start with "AC Immune surged 14.33% intraday..." Then the reason: "following the announcement of positive interim results from its Phase II VacSYn trial..." Mention the therapy's potential to slow Parkinson's progression. Include the 100% immunogenicity and safety. Maybe also note the common side effects. Then, a brief description of the company. Wait, the example in the prompt includes a sentence about the company's focus. So, after stating the reason for the price movement, add a sentence about the company's focus. Let me check the example again. The example has the surge, the reason (trial results), then a sentence about the company's focus. So I should follow that structure. Putting it all together: "AC Immune surged 14.33% intraday, following the announcement of positive interim results from its Phase II VacSYn trial, which showed the active immunotherapy ACI-7104.056 may slow Parkinson's progression with 100% immunogenicity and a favorable safety profile. The company is a clinical-stage biopharmaceutical firm focused on precision treatments for neurodegenerative diseases, primarily developing anti-alpha-synuclein active immunotherapies." Wait, but the example uses "with the company announcing..." while the user's example uses "with the company announcing..." So maybe start with "following the announcement..." instead of "with the company announcing...". Also, the example includes the trial details in the first part. Let me adjust accordingly. Also, the percentage is 14.33% as per rounding. The time period is intraday. The reason includes the trial results and the therapy's potential. The company's focus is mentioned in the second sentence. I think that's correct. Let me check for any missing key points. The trial's mid-term results, the therapy's effect on Parkinson's, the safety profile (no serious adverse events, 56% injection site reactions). The company's focus on neurodegenerative diseases and their main therapy. I should make sure the headline is concise but includes all required elements. Maybe combine the safety and immunogenicity into one part. Also, the example's output has a line break after the first paragraph. Should I do the same? The user's example shows a line break, but the rules don't specify. However, the example includes it, so maybe it's better to follow. Alternatively, keep it as a single paragraph. The user's example has a line break between the first and second sentences. Let me check the example again: "Pineapple Energy Inc. surged 4.23% in premarket trading, with the company announcing that its SunAtion subsidiary has signed an agreement to construct a 1.95MW project in New York City. The company stated that the project will be installed on a large industrial building, with construction scheduled.